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  Indian J Med Microbiol
 

Figure 3: Effects of extracts of BA on cytokine expression in RAW 264.7 cell line challenged with LPS. Code for sampling sources: IL-1βIL-1ing source BA: Bṛhat-Agnimantha, GJ 1: Gujarat sampling site 1, KA: Karnataka, MH: Maharashtra. Codes of Plant Parts: RB: Root bark, SB: Stem bark, LF: Leaves, YR-1, YR-1.5, YR-2 and YR-3: Young roots 12 months, young roots 18 months, young roots 24 months and young roots 36 months age respectively. Codes for extracts: 1: Petroleum benzene extract, 2: Ethyl acetate extract, 3: Ethanolic extract, 4: Aqueous extract. For example: B/KA/YR-1/2 denotes the ethyl acetate extract of 12-month-old Young roots of Bṛhat-Agnimantha drawn from Karnataka. Qualification criteria: A minimum 50% inhibition in pro-inflammatory cytokines (IL-1β, IL-6, and MIP-1α) or two-fold increase in expression of IL-2 (which is anti-inflammatory cytokine)

Figure 3: Effects of extracts of BA on cytokine expression in RAW 264.7 cell line challenged with LPS. Code for sampling sources: IL-1βIL-1ing source BA: <i>Bṛhat-Agnimantha</i>, GJ 1: Gujarat sampling site 1, KA: Karnataka, MH: Maharashtra. Codes of Plant Parts: RB: Root bark, SB: Stem bark, LF: Leaves, YR-1, YR-1.5, YR-2 and YR-3: Young roots 12 months, young roots 18 months, young roots 24 months and young roots 36 months age respectively. Codes for extracts: 1: Petroleum benzene extract, 2: Ethyl acetate extract, 3: Ethanolic extract, 4: Aqueous extract. For example: B/KA/YR-1/2 denotes the ethyl acetate extract of 12-month-old Young roots of Bṛhat-Agnimantha drawn from Karnataka. Qualification criteria: A minimum 50% inhibition in pro-inflammatory cytokines (IL-1β, IL-6, and MIP-1α) or two-fold increase in expression of IL-2 (which is anti-inflammatory cytokine)