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  Indian J Med Microbiol
 

Figure 2: Effects of Laghu Agnimantha on cytokine expression in RAW 264.7 cell line challenged with LPS. Code for sampling sources: L: Laghu, GJ1, 2, 3: Gujarat sampling sites 1, 2 or 3, KA: Karnataka, MP: Madhya Pradesh, OR1, OR2: Orissa sampling sites 1 or 2. Codes of plant parts: RB: Root bark, SB: Stem bark, LF: Leaves, YR-1, YR-1.5, YR-2, and YR-3: Young roots 12 months, Young roots 18 months, Young roots 24 months, and young roots 36 months age, respectively. Codes for extracts: 1: Petroleum benzene extract, 2: Ethyl acetate extract, 3: Ethanolic extract, 4: Aqueous extract. For example: L/GJ3/YR-3/2 denotes the ethyl acetate extract of 36-month-old Young roots of Laghu Agnimantha drawn from 3rd sampling site of Gujarat. Qualification Criteria: A minimum 50% inhibition in pro-inflammatory cytokines (IL-1β, IL-6, and MIP-1α) or two-fold increase in expression of IL-2 (which is anti-inflammatory cytokine)

Figure 2: Effects of <i>Laghu Agnimantha </i>on cytokine expression in RAW 264.7 cell line challenged with LPS. Code for sampling sources: <i>L: Laghu, </i>GJ1, 2, 3: Gujarat sampling sites 1, 2 or 3, KA: Karnataka, MP: Madhya Pradesh, OR1, OR2: Orissa sampling sites 1 or 2. Codes of plant parts: RB: Root bark, SB: Stem bark, LF: Leaves, YR-1, YR-1.5, YR-2, and YR-3: Young roots 12 months, Young roots 18 months, Young roots 24 months, and young roots 36 months age, respectively. Codes for extracts: 1: Petroleum benzene extract, 2: Ethyl acetate extract, 3: Ethanolic extract, 4: Aqueous extract. For example: L/GJ3/YR-3/2 denotes the ethyl acetate extract of 36-month-old Young roots of <i>Laghu Agnimantha</i> drawn from 3<sup>rd</sup> sampling site of Gujarat. Qualification Criteria: A minimum 50% inhibition in pro-inflammatory cytokines (IL-1β, IL-6, and MIP-1α) or two-fold increase in expression of IL-2 (which is anti-inflammatory cytokine)