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Figure 2: Retrospective versus prospective registration among subgroups. Numbers presented on each bar represents number of studies. (a) Type of study: post-marketing surveillance studies (n = 6: in which retrospective, n = 2; prospective, n = 4), bioavailability/bioequivalence (n = 1, prospective). (b) Study design: Nonrandomized studies (n = 16: in which retrospective, n = 13; prospective, n = 3), Other studies (n = 26: in which retrospective, n = 18; prospective, n = 8). (c) One study from 2013 enrolled both patients and healthy volunteers was registered retrospectively |
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