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   2012| October-December  | Volume 32 | Issue 2  
    Online since September 20, 2013

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Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study
Sampath K Vemula, Mukesh B Chawada, Kapil S Thakur, Mahesh K Vahalia
October-December 2012, 32(2):112-115
DOI:10.4103/0257-7941.118551  PMID:24167338
Context: Amlapitta Mishran suspension is a poly herbal ayurvedic formulation, which has been traditionally used for acidity and gastric ulcers. Aim: The aim of this study is to evaluate the antiulcer activity of Amlapitta Mishran on non-steroidal anti-inflammatory drugs (NSAID's) -induced ulcers in the rat model. Subjects and Methods: The antiulcer activity of Amlapitta Mishran was investigated on indomethacin (100 mg/kg) NSAID's induced ulcers in rats. Effect of two different doses of Amlapitta Mishran was studied by calculating the total number of ulcers, ulcer index and percentage inhibition. Statistical Analysis Used: Data was analyzed by the Student's t-test (P < 0.05). Results: Amlapitta Mishran treated rats have shown significant (P < 0.0001) decrease in the total number of ulcers and ulcer index and significant increase in % inhibition of ulcers as compared with positive control group. Conclusion: The results indicate that Amlapitta Mishran has showed a dose dependent antiulcer activity in experimental animals and confirms ayurvedic use of Amlapitta Mishran in gastric ulcers.
  9,205 210 6
Comparison of effect of Gayatri Mantra and Poem Chanting on Digit Letter Substitution Task
Balaram Pradhan, Seema Godse Derle
October-December 2012, 32(2):89-92
DOI:10.4103/0257-7941.118540  PMID:24167333
Context: Attention is one of the components to enhance academic excellence. Traditional techniques were included in Indian schools to develop mental faculties with a view to add value to the latter. Aim: The aim was to evaluate the effects of Gayatri mantra (GM) chanting on attention as measured by digit-letter substitution task (DLST). Settings and Design: School setting and self as control study design. Materials and Methods: Subjects consisted of 60 school students included (boys = 30 and girls = 30) in the age range of 12-14 years, who were trained for chanting GM for 5 days. They were assessed on DLST immediately before and after two sessions (i) GM chanting (10 min) and (ii) Poem line (PL) chanting with an equal duration (10 min). Fifty percent of participants performed GM chanting and remaining on the PL recitation on day 6. The orders of the sessions were reversed on day 7. Statistical Analysis Used: Repeated measure analysis of variance with Bonferroni adjustment used. Results: Both sessions showed significant improvement in the total and net score of DLST. The magnitude of net score improvement was greater after GM (21.67%) compared to PL (4.85%). Female group had found better performance following GM compared to PL chanting. Conclusions: Both GM and PL led to improvement in performance, as assessed by DLST. But the influence of GM had significantly higher than PL in net score of female group.
  6,204 523 5
Jeevani: Ayurveda for Women
Anita Mahapatra
October-December 2012, 32(2):120-122
  6,061 246 -
Ethnozoology of the Karbis of Assam, India: Use of ichthyofauna in traditional health-care practices
Valentina Teronpi, HT Singh, AK Tamuli, Robindra Teron
October-December 2012, 32(2):99-103
DOI:10.4103/0257-7941.118547  PMID:24167335
Background: Traditional or folk medicine is still prevalent among the Karbis as means of primary health-care. Traditional medicine is not only a source of healing, but the practice is also an important part of their religion and culture. Aim: The aim of the present study is to discuss the use of ichthyofauna in traditional health-care practices among the Karbis and other ethnic tribes of Karbi Anglong district, Assam. Setting and Design: Field study was undertaken from March 2011 to June 2012. A total of 75 informants were selected from 27 villages and the selection was based on their recognition as having sound knowledge relating to health-care practices. Materials and Methods: Information was collected following both unstructured and structured interview methods, group discussions and personal observation. Fish used in health-care practices were collected with the help of local guides and identified using available literatures. Results: The present study has recorded use of 14 species belonging 7 families in the treatment of 25 disease conditions. Traditional health-care practices of the Karbis include both local and oral applications and rituals to cure diseases. Use of fish to cure mental depression like symptoms locally referred as nihu kachingtung is prevalent until today. Studies among the Dimasa and Thadou tribes also revealed the use of fish in traditional medicine as therapies against different ailments, but do not use fish in rituals. Conclusion: Study on fish-based zootherapy could be a viable option for discovery of new compounds with therapeutic potentials. However, the attitude of the present generation towards traditional medicine as being unscientific and acculturation are the main causes of decline of such practice in the Karbis. Destructive fishing practices by poisoning water bodies with synthetic chemicals pose serious threats to aquatic fauna in the hill streams.
  5,196 261 8
Estimation of salivary and tongue coating pH on chewing household herbal leaves: A randomized controlled trial
Gayathri Ramesh, Ramesh Nagarajappa, AS Madhusudan, Nagarajappa Sandesh, Mehak Batra, Ashish Sharma, Srikant Ashwin Patel
October-December 2012, 32(2):69-75
DOI:10.4103/0257-7941.118531  PMID:24167330
Objectives: The purpose of the study was to evaluate saliva and tongue coating pH and also to assess the degree of tongue coating in healthy subjects before and after chewing herbal leaves (tulsi, mint, and curry leaf). Materials and Methods: A double-blind, randomized, concurrent, parallel-group study was conducted among 60 volunteer subjects, who were randomly assigned into three groups of 20 each (tulsi, mint, and curry leaf) and were asked to chew five to six fresh leaves of the respective plants twice daily for 7 days. Salivary and tongue coating pH were measured by a digital pH meter and color pH indicators. Data were analyzed statistically using repeated measure analysis of variance and Student's t-test. Results: Mean salivary pH values showed an increase immediately and 30 min after chewing the herbal leaves. A significant difference (P < 0.01) was observed between mint and curry leaf groups immediately after chewing and between tulsi and curry leaf groups (P < 0.05) 30 min after chewing the leaves. Tongue coating pH showed an increase toward alkalinity in all the groups. The assessment of tongue coating showed an increase in scores among tulsi and curry leaf groups, but this difference was not statistically significant. Conclusion: Chewing traditional medicinal plant leaves can be considered as safe, effective, and economical alternate options for maintaining good oral health.
  4,888 330 4
Pharmacognostic and phytochemical studies on Ficus Microcarpa L. fil
Mohan G Kalaskar, Sanjay J Surana
October-December 2012, 32(2):107-111
DOI:10.4103/0257-7941.118550  PMID:24167337
Background: Ficus microcarpa L. fil. (Syn: Ficus retusa) (Moraceae) is well-known traditional medicinal plant. The bark is used for diverse health ailments in traditional and folklore remedies. Aims: The present study was undertaken to lay down pharmacognostical and phytochemical standards. Materials and Methods: Pharmacognostic studies on fresh, dried and powdered bark was carried out to determine it's morphological, anatomical, and phytochemical diagnostic features. Furthermore, major phytoconstituents were identified from the extracts with the help of high performance liquid chromatography (HPLC) study. Results: The morphology showed to be soft, brittle, rough, shallow vertical, irregularly oriented fissures, curved surface; with splintering, laminated fracture. Microscopically F. microcarpa showed all general characteristics of bark with some distinct differentiation. The phellem is thin and even, phelloderm few cell and rectangular and followed by smaller sclerides, the phloem rays are broad, multi-serrate and showed the scattered bundles of sclerides. The fluorescence and physicochemical standards for bark were established. HPLC analysis showed the predominant presence of therapeutically important phytoconstituents such as oleanolic, betulinic acid, lupeol, β-sitosterol, catechin, and gallic acid. Conclusion: The bark of F. microcarpa considered equivalent to other Ficus species, such as Ficus virens, Ficus infectoria, Ficus arnottiana, Ficus lacor, and Ficus talboti. However, there is no pharmacognostical and phytochemical reports on F. microcarpa to authenticate and differentiate it from similar species. Present work has described pharmacognostical and phytochemical characteristics of F. microcarpa and diagnostic features to differentiate it.
  4,865 309 2
Immunomodulatory activity of Āmalaki Rasāyana: An experimental evaluation
Jignesh Rajani, BK Ashok, Galib , BJ Patgiri, PK Prajapati, B Ravishankar
October-December 2012, 32(2):93-98
Background: Ayurvedic system of medicine holds a number of drugs that improves the immunity. Āmalaki (Emblica officinalis) is one such drug. Researches with crude extracts of Āmalaki have proven the antioxidant and immunomodulatory activities. But, works on Āmalaki Rasāyana are not found reported. Aims: Considering this, two samples of Āmalaki Rasāyana (AR7 and AR21) were studied to evaluate comparative immunomodulatory activity against the cyclophosphamide immunosuppression in rats. Materials and Methods: Test drugs were prepared by following classical guidelines. Wistar strain albino rats of either sex were used in the study. Statistical Analysis: For comparison of data from cyclophosphamide control group with remaining cyclophosphamide plus test drug administered groups one way ANOVA with Dunnett's multiple t-test (DMTT) was employed. Results and Conclusions: Āmalaki Rasāyana possesses significant immunostimulant activity and moderate cytoprotective activity. AR21 was found to have better activity profile in terms of both immunostimulant as well as cytoprotective activity.
  4,435 383 -
Sexual dysfunction (Kṛcchra Vyavāya) in obesity (Sthaulya): Validation by an observational study
Parampalli Geetha, BS Aravind, G Pallavi, V Rajendra, Radhakrishna Rao, Naseema Akhtar
October-December 2012, 32(2):76-81
DOI:10.4103/0257-7941.118535  PMID:24167331
Objective: The present study intends to evaluate the relationship between Sthaulya (obesity) and Kcchra Vyavāya (sexual dysfunction) with respect to different phases of sexual intercourse through a single-centered, observational study in male patients of obesity. Materials and Methods: The study involved 33 obese males from the outpatient department of the Institution whose sexual functioning was assessed using an International Index of Erectile Function questionnaire, which was meant to assess five specific areas of sexual functioning. Results: A varying degree of sexual dysfunction was observed in four out of five areas of sexual functioning viz. erectile function (P < 0.02), orgasmic function (P < 0.02), sexual desire (P < 0.08), and overall satisfaction (P < 0.000) in obese individuals. Statistically significant dysfunction was not observed in intercourse satisfaction. Conclusions: Varying degree of sexual dysfunction is present in obese males, suggesting that obesity has a possible role in reducing the quality of sexual functioning in males as indicated in the classical ayurvedic literature.
  4,556 227 1
Nigella sativa extract affects conditioned place preference induced by morphine in rats
Milad Anvari, Atefeh Seddigh, Mohammad Naser Shafei, Hassan Rakhshandeh, Amir Hossein Talebi, Mohammad Reza Tahani, S Mohsen Saeedjalali, Mahmoud Hosseini
October-December 2012, 32(2):82-88
DOI:10.4103/0257-7941.118537  PMID:24167332
Objective: Neuroprotective, antioxidant, anticonvulsant, and analgesic effects of Nigella sativa (NS) have been previously shown. The interaction of NS with opioid system has also been reported. In the present study , the effects of NS hydro-alcoholic extract on the acquisition and expression of morphine-induced conditioned place preference (CPP) in rats were evaluated. Materials and Methods: CPP was induced by injection of morphine (5 mg/kg, i.p.) on three consecutive days in compartment A of the CPP apparatus. Injection of NS extract (200 and 400 mg/kg, i.p.) 60 min before morphine administration on the conditioning days and 60 min before the post-conditioning phase was done for the evaluation of acquisition and expression effects, respectively. Conditioning effect of NS extract was also evaluated by injection of extract (200 or 400 mg/kg, i.p.) in the conditioning phase, instead of morphine in different groups. The difference in time which the animals spent in compartment A on the day before conditioning and the days after conditioning was determined and compared between groups. Results: The time spent by the rats in compartment A in the morphine group was greater than that in the saline group (P < 0.01). Both doses of NS extract decreased acquisition of morphine-induced CPP (P < 0.01 and P < 0.001), but had no significant effect on the expression of morphine CPP. Higher dose of the extract (400 mg) showed a significant conditioning effect which was comparable to the effect of morphine. Conclusion: The results of the present study showed that the hydro-alcoholic extract of NS has conditioning effect. It also decreased acquisition, but had no significant effect on the expression of morphine CPP.
  4,382 175 4
Quality control for Tamra (copper) Bhasma
Somsri Wiwanitkit, Viroj Wiwanitkit
October-December 2012, 32(2):126-126
DOI:10.4103/0257-7941.118555  PMID:24167341
  3,656 215 -
Role of Sadyo Vamana in dental abscess (danta arbuda)
Narra Vijayalakshmi
October-December 2012, 32(2):104-106
DOI:10.4103/0257-7941.118548  PMID:24167336
Sadyo Vamana is a type of purificatory measure mentioned in Ayurveda, which to expel the pus and morbid factors present in a dental abscess without opening it. However, Sadyo Vamana's role in fever and pus filled dental abscess has not been reported so far. I report a case of dental abscess with fever. A 24-year-old male patient with a pus filled dental abscess. His fever and dental abscess didn't respond to antibiotic and analgesic treatment for 10 days. The patient was given Sadyo Vamana (instant therapeutic emesis) to expel the accumulated pus in dental abscess without opening it. The patient got complete relief from fever and dental abscess after Sadyo Vamana. The patient not gave internal medication.
  3,358 193 -
Capacity building of AYUSH practitioners to study the feasibility of their involvement in non-communicable disease prevention and control
Dinesh Kumar, Sunil Kumar Raina, AK Bhardwaj, Vishav Chander
October-December 2012, 32(2):116-119
Background: Sharing of public health knowledge and skills by professionals in allopathic system of medicine with Ayurveda, Yoga, and Naturopathy, Unani, Siddha and Homeopathy (AYUSH) professionals in India has always been considered as part of integrating the health system in India. But till date, a curriculum has not been framed for follow-up. Materials and Methods: A training course was developed for AYUSH professionals in India on the public health principles for the prevention and control of non-communicable diseases (NCDs). Three course chairs interacted with international and national public health and AYUSH experts, and the curriculum for a 3-month course was developed. Results: The curriculum comprised interactive lectures, problem-based exercise, field visits, and research protocol development. A total of four participants, nominated by the World Health Organization, India, were trained during the course, with significant ( P = 0.00) improvement in knowledge from 53.2 to 80.0 points. Conclusion: A novel and feasible public health course for complementary and alternative medicine professionals on the public health principles for NCDs' prevention and control is needed to bridge the demand gap for public health professionals in India.
  3,137 196 -
Critical review and validation of the concept of Āma
P Ram Manohar
October-December 2012, 32(2):67-68
DOI:10.4103/0257-7941.118524  PMID:24167329
  2,957 293 2
Ayurvedic Point, translating tradition into modernity
Antonio Morandi, Carmen Tosto
October-December 2012, 32(2):123-125
DOI:10.4103/0257-7941.118554  PMID:24167340
  2,890 127 -

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