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   2007| October-December  | Volume 27 | Issue 2  
    Online since November 11, 2011

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Pharmacological validation of Kantha chendooram for antiulcer activity in modified pylorus ligated (shay) rat model
R Vadivelan, K Elango, B Suresh, BR Ramesh, S Bhadra, A Raghuram, R Sampathkumar
October-December 2007, 27(2):38-43
The use of metals and minerals is predominant in siddha system of medicine. As per siddha concept, peptic ulcer is known as Valigunmam, the basic abnormality appears to be the derangement of metabolism in the stomach and duodenum resulting in malfunctioning of the secretory process of gastric mucosa. Chendooram is a group of siddha drugs which is used for anemia, obesity, rheumatic diseases; abdominal tumours etc.During the present study standardized Kantha chendooram was selected and evaluated for its anti-ulcer activity, which could not be attempted by researchers earlier.
[ABSTRACT]   Full text not available  [PDF]
  751 80 -
Netra darpanamu - A Unique book on eye diseases
Goli Penchala Prasad
October-December 2007, 27(2):44-49
Netra Darpanamu  is the only book written exclusively on Eye diseases in Telugu. This Ayurvedic  book, which is famous in Andhra Pradesh, was first published in 1908 in Eluru. The book is written in chaste Telugu poetry, comprising the types of treatment followed by 36 recipes. This book contains names of various eye diseases, treatment procedures like bandages, plasters, collyriums and regimen of food and behaviour. This article aims to highlight the importance of this book in treating various eye diseases.
[ABSTRACT]   Full text not available  [PDF]
  733 65 -
Comparative antimicrobial activities of Emblica officinalis and Ocimum sanctum
S Vijayalakshmi, V Arunkumar, D Anju, P Gunasundari, P Moorthy, AK Chandrasekharan
October-December 2007, 27(2):1-6
The aqueous and successive extracts of the fruit pulp of Emblica officinalis  and fresh leaves and stems of Ocimum sanctum  were prepared and evaluated for antimicrobial activity. The successive extracts such as petroleum ether,chloroform, ethyl acetate and methanol were prepared by successive solvent extraction method and aqueous extract by maceration process and screened for antimicrobial activity against gram positive bacteria Staphylococcus aureus,  gram negative bacteria E.coli  and fungal strains of Candida  species by using agar cup plate method. The extracts showed different degree of activity against pathogenic microbes. The results obtained were compared with standard drugs Amoxicillin (10μg) and Amphotericin B(10μg). The methanolic extract of Emblica officinalis  was found to be more effective than the leaf and stem extracts of Ocimum sanctum  in inhibiting all the microbial strains.
[ABSTRACT]   Full text not available  [PDF]
  717 67 -
Analgesic activity of Justicia beddomei leaf extract
U Srinivasa, J Venkateshwara Rao, AM Krupanidhi, S Shanmukhappa
October-December 2007, 27(2):14-18
The analgesic activity of ethanolic extract of Justicia beddomei  leaves (Family: Acanthaceae) was evaluated in albino rats using Eddy's hot plate method. The extract at 50 and 100 mg/ kg, (i.p), showed significant analgesic activity at 90 minutes of administration. The analgesic effect of the extract was comparable to that of morphine sulphate.
[ABSTRACT]   Full text not available  [PDF]
  704 75 -
Effect of Syzygium calophyllifolium Walp. seed extract on transaminases and phosphatases in alloxan induced diabetic rats
K Gurusamy, R Kokilavani, KS Ananta Teepa
October-December 2007, 27(2):28-33
The antidiabetic effect of an aqueous seed extract of Syzygium calophyllifolium  Walp.was studied in alloxan induced diabetic rats. Changes in serum and tissue AST, ALT LDH, ACP and ALP, enzymes activities in alloxan induced rats were studied and found to be reversed by the oral administration of S.calophyllifolium  seed extract.
[ABSTRACT]   Full text not available  [PDF]
  691 68 -
Ethnomedicinal investigation in Nandurbar district of Maharasthtra
YA Ahirrao, DA Patil
October-December 2007, 27(2):50-56
The aborigines exploit medicinal virtues of tubers, roots fruits, seeds, flowers, leaves etc. from the forest and use in a variety of ways. The are used in the form of juice, decoction, oil, paste, extract, infusion and powder. Fresh parts are also used and the substances like sugar, sugarcandy, groundnut oil, milk and cow-ghee are used as additives. The native uses of medicinal plants are employed to better stomachcomplaints, rheumatic pains, spermatorrhoea, tooth-ache, head-ache, ear-ache, weakness, urinal troubles, fresh cuts, tumors, fever, mouth ulcer, bone fracture and few other human diseases. Total 47 species are being reported for the aforesaid ailments of these, applications of 32 species are unknown or little known. These are, however, desired for further scientific assessments for obvious reasons.
[ABSTRACT]   Full text not available  [PDF]
  683 69 -
Diuretic activity of Nyctanthes arbortristis Linn.
D Sasmal, Sanjita Das, SP Basu
October-December 2007, 27(2):19-23
Nyctanthes arbortristis  Linn. is a well documented plant. The present study is done to establish the diuretic activity of the water-soluble portions of the ethanolic extracts of its flowers, barks, seeds and leaves. In toxicity study, the extracts were seen to be safe up to the dose of 2.0 gm/kg. For the estimation of diuretic activity, the parameters studied were total urine volume and urine concentration of Na + , K +  and Cl - . The ethanolic extracts of different plant parts of Nyctanthes arbortristis  L. possess significant diuretic activity as reflected by rise in urine volume with cation excretion. The ethanolic extracts of the seeds and leaves at their higher doses exhibited higher electrolyte excretion.
[ABSTRACT]   Full text not available  [PDF]
  683 68 -
Hypoglycemic and Hypolipidemic effect of Coccinia indica Wight & Arn in alloxan induced diabetic rats
S Manjula, B Ragavan
October-December 2007, 27(2):34-37
Diabetes Mellitus is characterized by elevated plasma glucose concentrations resulting from insufficient insulin. The present study was aimed to investigate the hypolipidemic effect of Coccinia indica  aqueous leaf extract in alloxan induced diabetic rats. The results of this study revealed that a continuous administration of Coccinia indica  extract for 21 days prevents the elevation of the level of serum lipids secondary to the diabetes state
[ABSTRACT]   Full text not available  [PDF]
  684 64 -
A comparative pharmacognostical evaluation of two Artemisia species found in Nilgiris biosphere
J Suresh, K Elango, SP Dhanabal, N Paramakrishnan, B Suresh
October-December 2007, 27(2):7-13
Artemisia pallens  Wall. ex DC commonly known as "Davana"in Kannada and Artemisia abrotanum  Linn. known as "Southernwood" (Asteraceae) are aromatic herbs, erect in habit, upto 60 cm tall, leaves are very small, much divided, bluish green. These plants find use in traditional systems of medicine viz., anthelmintic, tonic and antipyretic properties. Since, these species have not been scientifically evaluated; the present study was aimed to bring these plants under a suitable pharmacognostical scheme.
[ABSTRACT]   Full text not available  [PDF]
  685 57 -
Effect of Semecarpus anacardium against lead induced toxicity in rats
N Abirami, V Shanmuga Raju, K Rajathi
October-December 2007, 27(2):24-27
The present study was carried out to understand the antioxidant and protective effect of Semecarpus anacardium  against lead acetate induced toxicity. This was done by analyzing the phytochemicals (Flavanoids, alkaloids, resins, tannins, carbohydrates, proteins, etc.) present in the plant and by assessing the hepatoprotective efficacy of the plant against lead acetate induced albino rats. Histopathological examination was also carried out to have a supporting evidence for the study. It was observed that the nut milk extract contains flavanoids, phenols and carbohydrates and the drug was effective against lead acetate induced toxicity. The levels of the marker enzymes were increased in the lead acetate induced rats and after the treatment of Semecarpus anacardium  the liver damage decreased.
[ABSTRACT]   Full text not available  [PDF]
  661 65 -