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2009| April-June | Volume 28 | Issue 4
Online since
November 11, 2011
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ARTICLES
Preliminary phytochemical screening and antimicrobial studies on
Artocarpus lakoocha
Roxb.
Anima Pandey, SP Bhatnagar
April-June 2009, 28(4):21-24
PMID
:22557328
The antibacterial activity of
Artocarpus lakoocha
Roxb. bark was tested against different species of bacteria. The minimum inhibitory concentration (MIC) of the methanolic extract showed that there was no growth in Shigella soneii 2, E.coli MTCC 1568, Bacillus pumilus 8241, Proteus mirabilis AM 198, Bacillus subtelis ATCC 6633,
E. Coli
Row 7/12 Species at 200-400g/ml. From the result obtained, it was observed that the methanolic extract of.
Artocarpus lakoocha
at concentration of 200 gl ml and 400 gl ml exhibited a good activity against gram negative bacteria.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
952
111
-
In-vitro
anti- inflammatory activity of aqueous extract of leaves of
Plectranthus amboinicus
(Lour.) Spreng
VR Ravikumar, M Dhanamani, T Sudhamani
April-June 2009, 28(4):7-9
PMID
:22557324
Aqueous extract of leaves of Plectranthus amboinicus (lour.) Spreng, which is traditionally used in the treatment of cough and cold was screened for its anti- inflammatory activity by HRBC membrane stabilisation model. Aqueous extract (500 mcg/ml) showed significant anti-inflammatory activity as compared to that of hydrocortisone sodium.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
879
112
-
In vitro
antioxidant activity of selected antiasthmatic herbal constituents
P Nilani, N Kasthuribai, B Duraisamy, P Dhamodaran, S Ravichandran, K Ilango, B Suresh
April-June 2009, 28(4):3-6
PMID
:22557323
Asthmatic patients are more subjected to continuous oxidative stress. Roosting the antioxidant defenses of asthma patient could be beneficial as it may help thwart symptoms of the lung disease and asthma. Considering these facts different plant extracts and phytoconstituents with proven anti asthmatic property had been subjected to antioxidant study at various combinations using Diphenyl Vicryl Hydrazyl radical scavenging method, Hydrogen Peroxide radical scavenging method, Nitric oxide radical inhibition method, ABTS radical scavenging method and Lipid peroxidation assay method. All the selected herbal based constituents and extracts at different combination showed a potent antioxidant activiy by Nitric oxide radical inhibition activiy method followed by ABTS method. The present finding suggests that the selected plant based anti asthmatic constituents namely Coleus extract (10% Forskolin), Piper longum extract (20% Piperine), CurcuminC3Complex (60% Curcumin), Vasaka (30% Vasicinone), Forskolin (95%), Pperine (98%), Curcumin C3 Complex (98.5%) and Vasicinone (75%) could be utilised in alternate anti asthmatic therapy, since they play a vital role in scavenging Nitric oxide which could prevent the bronchial inflammation in asthmatic patients.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
875
104
-
A Study of hepatoprotective activity of
Hedyotis corymbosa.
Linn, in albino rats
Rajshekar Chimkode, MB Patil, Sunil Jalalpure, TY Pasha, Sibaji sarkar
April-June 2009, 28(4):32-35
PMID
:22557330
Hedyotis corymbosa
Linn is spreading, suffruticose annual, belongs to family Rubiaceae frequently met with in field through out India, usually during rainy season. This plant is used for their medicinal properties as a folk medicine to treat jaundice, mouth wash in toothache. Hence the present study was aimed to investigate the hepatoprotective activity of ethanolic extract of
Hedyotis corymbosa
which was separated in to different fractions against carbon tetrachloride intoxification. The results indicate that, Intoxification with CCl
4
increase the levels of SGOT and SGPT. The elevated levels of SGOT and SGPTwere significantly decreased by ether and butanol fractions at P<0.001 and butanone and ethanol at p<0.05, where as petroleum ether and ethyl acetate did not shown any significant reduction in the level of SGOT and SGPT.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
843
96
-
Antimicrobial activities of
Ichnocarpus frutescens
(L.) R.Br. and
Hemidesmus indicus
R.Br. Roots
NS Malathy, S Sini
April-June 2009, 28(4):13-15
PMID
:22557326
Hexane, chloroform and aqueous extracts from Hemidesmus indicus and Ichnocarpus frutescens roots were evaluated for their antimicrobial activity. The chloroform extract of both plants showed antibacterial and antifungal activities against the tested organisms. Both the plants showed highest antibacterial and antifungal activity against Eschericia coli and Aspergillus flavus respectively. With increase in concentration of the extract a corresponding increase in diameter of inhibition vgme was observed. The roots of the common substitute of H.Indicus namely Ifrutescenspossess similar antimicrobial properties.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
840
98
-
Formulation development and in vitro antioxidant studies of
Churnas
containing natural sweetener and nutraceutical
VR Salunkhe, SB Bhise
April-June 2009, 28(4):25-31
PMID
:22557329
Gymnema sylvestre, Curcuma longa, Azadiracta indica, Aegle marmelos, Salacia chinensis, Emblica officinalis were used as active components and Stevia rebaudiana as natural sweetener with nutraceuticalfor development of
Churnas
. The free radical scavengingpotential of
Churnas
was studied by using different antioxidant models of screening. The hydroalcoholic extract of sweet and bitter
Churnas
at 500μg/ ml showed maximum scavenging of the riboflavin NET system, DPPH and total antioxidant capacity. However, the extract showed only moderate scavenging activity of nitric oxide radicals and iron chelation. This could be due to higher phenolic content in the extract. Sweetness potency of
Churna
was found to be appropriate sweet, acceptable and palatable. These observations can be useful for the justifications of various ingredients and therapeutic applications of the
Churnas
.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
842
85
-
Antibacterial Activity of
Leptadenia reticulata
(Retz.) Wight. & Arn. (Asclepidaceae)
C Kalidass, M Glory, Francis Borgio, VS Manickam
April-June 2009, 28(4):10-12
PMID
:22557325
leptadenia reticulata of Asclepidaceae family is a shrub, originally property of Petroleum ether, Alcohol & Chloroform extract of
L. reticulata
. The antimicrobial testing was carried out by "Disc diffusion method". Amongst the tested three extracts, chloroform extract showed high antimicrobial activity against
E. coli
, alcoholic extract showed high antibacterial activity against Pseudomonas aeruginosa, while Petroleum ether extract showed antibacterial activity against Klebsilla pneumonae
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
798
75
-
Phytochemical observation and antibacterial activity of
Cyperus esculentus
L.
N Prakash, B Ragavan
April-June 2009, 28(4):16-20
PMID
:22557327
In the present study various extracts of
Cyperus esculentus
L. such as acetone, 50% ethanol, chloroform and petroleum ether were evaluated for their antibacterial activity against several human pathogens such as Escherichia coli, Staphylococcus aureus, Salmonella sp, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa and Citrobacter freundii, by using disc diffusion method. The activity of the samples were compared with that of standard antibiotics. The qualitative phytochemical analysis was also carried out with all the extracts of the sample. Of all the extracts 50%*nbsp; ethanol and acetone extract were found to be rich in phytochemicals such as alkaloids, flavonoids, phenols, tannins, steroids, terpenoids and glycosides. Acetone extract showed highest inhibitory activity against
S.aureus
, ILpneumoniae and P.vulgaris. 50% ethanolic extract showed maximum activity against PL.coli, S.aureus and Salmonella sp. Chloroform extract maximally inhibited the growth of S.aureus whereas, petroleum ether extract showed positive results against Salmonella sp respectively. All extracts were sensitive to
C. freundii
.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
777
81
-
Wound healing properties of
Artocarpus heterophyllus
Lam
Nilesh Gupta, UK Jain, AK Pathak
April-June 2009, 28(4):36-37
PMID
:22557331
The studies on excision wound healing model reveals significant wound healing activity of the methanolic leaf extract (simple ointment 5%) of "
Artocarpus heterophyllus
" ham which is comparable with standard (Betadine). In the excision model, the period of epithelization, of the extract treated group was found to be higher than the controlgroup and slightly lesser than standard treated group of animals on the up to 16
th
post wounding day.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
745
89
-
Traditional herbal remedies in Buldhana District (Maharashtra, India)
Ya Ahirrao, PS Patil, UP Aher, YA Dusing, DA Patil
April-June 2009, 28(4):38-41
PMID
:22557332
The paper documents traditional herbal remedies from buldhana district of Maharashtra (India). The plant parts most commonly used are bark, leaves, flowers, fruits and seeds, apart from plant products like latex and gum. The medicaments include recipes like decoction, infusion, paste, ash, extract juice, besides gum and latex. There are mainly used afresh. Occasionally, these are supplemented by domestic edible substances of plant-origin. The reliance on herbal medicines for healthcare is associated with traditional belief of effectiveness as well as poor economic status. Role of homestead gardens in native phytotherapy is being focused for the first time from this region. The first-hand information adduced is desired to divulge new lead molecules or will add new sources of herbal medicine.
[ABSTRACT]
Full text not available
[PDF]
[PubMed]
742
80
-
From the Founding Editor
PR Krishnakumar
April-June 2009, 28(4):1-1
PMID
:22557322
Full text not available
[PDF]
[PubMed]
489
55
-
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Online since 25 September, 2011