Siddha system of medicine is one of the oldest medical system of India. Existed separately in early times. Although this system declined in later years., in the wake of changing mode of life modern medicine, it continued to sustain its influence on the masses Parpam is a group of siddha drugs, which is used in diarrhea, colic, pepticulcer, asthma, chronic cough tuberculosis, etc. During the present study Sangu Parpam and silasathu Parpam were selected and evaluated for its antiulcer effect in albino rats, which could not be attempted by researchers earlier.

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An intensive survey was carried out in Wynadu, Palghat and malappuram districts of Kerala to identify plants used by the tribals were identified in the survey. A brief account of 15 plant species used as single plant remedy for alleviating liver ailments by the tribals is given in this report. This ethnomedical information can lead the development of useful drugs against liver diseases.

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The alcoholic extract of Achyranthes bidentata (AAB) has been studied for analgesic, anticonvulsant and CNS depressant activities in animal models. Analgesic activity was studied using acetic acid-induced writing test for assessing peripheral analgesic effect and tail immersion test for central analgesic effect. Anticonvulsant activity was performed by maximal electroshock induced convulsions; while the locomotor activity was evaluated using actophotometer. AAB (250-500 mg/kg) significantly reduced the number of wriths induced by acetic acid and elevated pain threshold in hot water test. The extract (500mg/kg) exhibited anticonvulsant activity significantly (P<0.001) against tonic seizures induced by MES. The results of locomotor activity showed the significant (P<0.01) CNS depressant effect at the three doses (250,375 and mg/kg) employed. The results suggest that AAB exhibited analgesic, anticonvulsant and CNS depressant activity in a dose dependent pattern.

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Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13.

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Sida acuta Burm.f. (Fam. Malvaceae) is used in Siddha system of medicine and in folk medical practice in Tamil Nadu under the names Arivalmooku pachilai or vattatiruppi. The leaves of this plant are used for their diuretic, demulcent, anthelmintic and wound healing properties. The present paper discusses the anatomy of petiole leaf and stem, microscopic constants, physico-chemical standards and fluorescence analysis of the drug.

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The plant Coldenia procumbens Linn.  is used commonly in Indian system of medicine for various ailments. The present paper deals with detailed pharmacognosy of the leaf of coldenia procumbens Linn. and includes its Macro/Micro morphological (vein islet, vein termination numbers and stomatal index) anatomical characters, Physico chemical standards such as ash values, extractive values, crude fibre content and fluorescence characters of various extracts and leaf powder after treatment with different chemical reagents under UV light. Prelimanary phytochemical tests on various extracts of the leaf have also been carried out.

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