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REVIEW ARTICLES
Tinospora cordifolia
: One plant, many roles
Soham Saha, Shyamasree Ghosh
April-June 2012, 31(4):151-159
DOI
:10.4103/0257-7941.107344
PMID
:23661861
Natural products with medicinal value are gradually gaining importance in clinical research due to their well-known property of no side effects as compared to drugs.
Tinospora
cordifolia
commonly named as "Guduchi" is known for its immense application in the treatment of various diseases in the traditional ayurvedic literature. Recently the discovery of active components from the plant and their biological function in disease control has led to active interest in the plant across the globe. Our present study in this review encompasses (i) the genetic diversity of the plant and (ii) active components isolated from the plant and their biological role in disease targeting. The future scope of the review remains in exploiting the biochemical and signaling pathways affected by the compounds isolated from
Tinospora
so as to enable new and effective formulation in disease eradication.
[ABSTRACT]
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[PubMed]
23,888
2,858
112
BOOK REVIEW
The 'Pāka
darpaṇam
': The text on Indian cookery by King Nala
Naveen Kodlady
April-June 2014, 33(4):259-262
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20,633
763
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EDITORIAL
Scope of
ayurveda biology
in the future of integrative healthcare for global wellness
Chethala N Vishnuprasad
January-March 2018, 37(3):117-119
DOI
:10.4103/asl.ASL_1_20
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13,966
539
1
ORIGINAL ARTICLES
Estimation of total alkaloid in
Chitrakadivati
by UV-Spectrophotometer
Manjunath Ajanal, Mahadev B Gundkalle, Shradda U Nayak
April-June 2012, 31(4):198-201
DOI
:10.4103/0257-7941.107361
PMID
:23661869
Background:
Herbal formulation standardization by adopting newer technique is need of the hour in the field of Ayurvedic pharmaceutical industry. As very few reports exist. These kind of studies would certainly widen the herbal research area. Chitrakadivati is one such popular herbal formulation used in Ayurveda. Many of its ingredients are known for presence of alkaloids.
Methodology:
Presence of alkaloid was tested qualitatively by Dragondroff's method then subjected to quantitative estimation by UV-Spectrophotometer. This method is based on the reaction between alkaloid and bromocresol green (BCG).
Results and Conclusion:
Study discloses that out of 16 ingredients, 9 contain alkaloid. Chitrakadivati has shown 0.16% of concentration of alkaloid and which is significantly higher than it's individual ingredients.
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13,211
1,294
46
REVIEW ARTICLES
Identity of
Ṭaṅkārī
(
Physalis Minima
Linn.) in Ayurvedic Classics: A Literature Review
Supriya S Kallianpur, Rohit A Gokarn, N Rajashekhar
July-September 2016, 36(1):6-11
DOI
:10.4103/0257-7941.195408
PMID
:28182025
Proper identification of drugs and their use in proper doses are important for successful treatment.
Physalis minima
Linn commonly known as country gooseberry has anti-cancerous, anti-diabetic, analgesic, antipyretic and anti-inflammatory potentials. The present paper is aimed to ascertain the proper identity of
Ṭaṅkārī
(
Physalis minima
Linn.) in Ayurvedic classics by a meticulous search and hence a review of the drug
Ṭaṅkārī
(
Physalis minima
Linn) was carried out in the texts of Ayurveda, modern literature, journals and online publications. The result of the search showed that the name “
Ṭaṅkārī
” is not found in Vedic lore. In Saṃhitās, it is mentioned in Bhāvaprakāśa. Reference of the drug “
Śārṅgeṣṭhā
” is found in Bṛhattrayī, Bhela, Kāśyapa, Cakradatta and Vaṅgasena. It is variously named as
Cirapoṭikā
,
Kākatikta
, and
Vāyasī
by ḍalhaṇa and he describes it as gaura (pale), vartula (round), and as having
avaguṇṭhita
/
veṣṭhita
(covered) fruit which matches the description of
Ṭaṅkārī
(
P. minima
Linn). A search for terms
Kākatikta
and
Vāyasī
showed
Kākatikta
to be synonymous to
Śārṅgeṣṭhā
and
Vāyasī
to be synonymous to both
Kākatikta
and
Kākamācī
(
Solanum nigrum
). Madanapāla and Śāligrāma Nighaṇṭus have mentioned the name
Cirapoṭikā
to be synonymous with
Ṭaṅkārī
. Śodhala has used the term Parpoṭī as a synonym of
Ṭaṅkārī
, which is the Gujarati name of
P. minima
Linn. Recent authors have considered
Śārṅgeṣṭhā
as either
P. minima
or
Cardiospermum helicabum
. The regional names of
P. minima
are
Cirpoṭi
(Hindi),
Cirboli
(Marathi), also the folklore uses and pharmacological activities of
P. minima
are in accordance with the indications of
Śārṅgeṣṭhā
in classics. Thus with a complete review of both Ayurveda and modern literatures, it can be concluded that the drug mentioned as
Ṭaṅkārī
in Bhāvaprakāśa is the same as
Śārṅgeṣṭhā
mentioned in the classics.
Cirapoṭikā
and
Kākatikta
are its synonyms.
Cardiospermum helicabum
is
Karṇaspoṭha
, and hence
Śārṅgeṣṭhā
of classics is
P. minima
which is supported by the regional names, pharmacological activity and folklore claims.
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3
ORIGINAL ARTICLE
Evaluation of Ratnaprash for its effect on strength, stamina and fatigue using swim endurance test and biochemical estimation in swiss albino mice
Arun Gupta, Satyendra Kumar, Rashmi Rajput, Ruchi Srivastava, Rajiv K Rai, J. L. N. Sastry
July-September 2015, 35(1):26-31
DOI
:10.4103/0257-7941.165626
PMID
:26600664
Context:
Traditional medicines have been considered as important resources for postponing fatigue, accelerating elimination of fatigue related metabolites and improving physical ability.
Rasāyanās
or rejuvenative therapies are mentioned as one of the eight clinical specialties in Ayurveda for attaining longevity, healthy life and regulation of bodily balance. Eventhough more detailed studies are needed to confirm the claims of benefits in the light of evidence based research, Ratnaprash, a herbo-mineral
rasāyana
formulation, is proposed here to be an antifatigue supplement that is good in promoting strength and stamina.
Materials and Methods:
In the present study, anti fatigue, strength and stamina enhancing properties of Ratnaprash were examined based on swim endurance capacity and the change in biochemical parameters in Swiss Albino mice. Treatment groups were orally administered Ratnaprash at various test doses (500, 1000, 2000 mg/Kg per day), while the control group received distilled water at similar dose volumes. Effect of therapy was evaluated after 28 days of treatment.
Results:
At the end of study period, the swimming times to exhaustion were longer in the treated groups than in the control group. Plasma lactate levels of treated groups were lower than those of the control group (
P
< 0.05) while tissue ATP levels were higher. These effects were dose dependent and the strongest effect was seen in groups treated at 1000 mg/Kg.
Conclusion:
Ratnaprash enhanced the forced swimming capacity of mice and exhibited elevated anti-fatigue activity, reduced blood lactate levels and increased tissue ATP levels in preclinical models in comparison to vehicle control, exhibiting possible role in increasing strength and stamina and contributing anti-fatigue activity.
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14,064
225
1
ARTICLES
Ancient concept of metal pharmacology based on Ayurvedic literature
Prasanta Kumar Sarkar, Sanjita Das, PK Prajapati
April-June 2010, 29(4):1-6
PMID
:22557360
Metals have had a long history in Ayurvedic system of medicine. Mercury (Parada), gold (Swarna), silver (Rajata), copper (Tamra), iron (Lauha), tin (Vanga), lead (Naga), and zinc (Yasada) are used in therapeutics in an incinerated (Bhasma) form. The pharmacological actions, therapeutic indications, adverse effects and management of adverse effects of these metals are described and emphasis has been given to the proper preparation, rational dose and duration during clinical practice in the classics of Ayurveda. Most important observation is, there are no contraindications of these Bhasmas, indicating universal applicability to all age levels with suitable adjuvant, proper dose and duration.
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ORIGINAL ARTICLES
Preliminary physicochemical evaluation of
Kushta-e-Aahar Mohra
: A unique formulation of Unani medicine
Mohd Akhtar Ali, Hamiduddin , Mohammad Zaigham, Mohammad Ikram, Mohd Shadab, Gazi Jahangeer Rather
January-March 2018, 37(3):127-132
DOI
:10.4103/asl.ASL_145_17
Introduction:
Zahar Mohra
(Serpentine/Bezoar stone) is mentioned as efficacious and a useful drug indicated in heart diseases in Unani medicine. It is also used to remove effect of poison and is termed in
Unani Medicine
as
Daf-e-Zahar
or
Fad-e-Zahar
(antidote). It acts as preservative of
quwa
(faculty) and
ruh
(pneuma).
Unani
physicians commonly use
Zahar Mohra
(ZM) in
Kushta
(Calcined) form, because the
Kushta
gives quick and potent response. In this work owing to its beneficial and efficacious use,
Kushta-e-Zahar Mohra
(KZM) was prepared as per contemporary methods and was subjected to preliminary physicochemical analysis to develop a standard.
Materials and Methods:
KZM was prepared as per contemporary method (Muffle furnace) by simulation of the heat pattern as per classical texts/method and its physico-chemical and instrumental analysis including XRD, ICP-MS and AAS was performed. Statistical analysis used was Mean ± SEM.
Results:
Prepared
Kushta
passes the classical Unani specification tests, contemporary test data for various physicochemical parameters were also set in. XRD analysis indicated presence of Mg
2
Si O
4
(Magnesium Silicate) and Ca (Cl O)
2
. 3H
2
O (Calcium Chlorite Hydrate) phase.
Conclusions:
The study indicates content and physicochemical standards of KZM prepared by contemporary method; it can be a better choice. KZM can be safe for use as acclaimed for heart diseases in
Unani
System of Medicine.
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REVIEW ARTICLES
Effects of various
Prāṇāyāma
on cardiovascular and autonomic variables
L Nivethitha, A Mooventhan, NK Manjunath
October-December 2016, 36(2):72-77
DOI
:10.4103/asl.ASL_178_16
PMID
:28446827
Cardiovascular functions are controlled by neural factors, temperature, hormones, etc., Of these, neural factors primarily concern the autonomic nervous system, which plays a major role in maintaining and regulating cardiac functions, e.g., blood pressure and heart rate.
Prāṇāyāma
is one of the most important yogic practices. There are various review articles on Yoga and its effects but, though
Prāṇāyāma
is a part of yoga, there is lack of review articles. To the best of our knowledge there is no known review article on effect of various
Prāṇāyāma
on cardiovascular and autonomic variables. To provide a general overview about the effect of various
prāṇāyāma
(breathing techniques) on cardiovascular and autonomic variables. A narrative review was performed based on the available scientific literature. An electronic data search was performed in Medline/PubMed database to review relevant articles, using keywords such as “
Prāṇāyāma
, Yogic breathing techniques, Unilateral nostril breathing, Alternate nostril breathing,
Kapalbhati
,
Bhastrika
and
Bhramari Pranayama
”. All the relevant articles published from 1988 to 06-04-2016 were included in this review. Slow type of yogic breathing technique was reported to produce beneficial effect on cardiovascular and autonomic variables while fast breathing techniques do not produce such effects. There is lack of consistency in the results of specific nostril yogic breathing techniques and the mechanisms behind the effects of various
prāṇāyāma
. This review suggests that different types of
Prāṇāyāma
techniques produce different effects and the mechanisms behind these effects are not fully understood.
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REVIEW ARTICLE
A review on phyto‑pharmacological potentials of
Euphorbia thymifolia
L.
Prashant Y Mali, Shital S Panchal
January-March 2013, 32(3):165-172
DOI
:10.4103/0257-7941.123001
PMID
:24501446
Euphorbia
thymifolia
L. (
Euphorbiaceae
) is a small branched, hispidly pubescent, prostate annual herb, commonly known as
laghududhika
or
choti
-
dudhi
. The leaves, seeds and fresh juice of whole plant are used in worm infections, as stimulant, astringent. It is also used in bowel complaints and in many more diseases therapeutically. The present work is an extensive review of published literature concerning phytochemical and pharmacological potential of
E.
thymifolia
. Data was searched and designed using various review modalities manually and using electronic search engines with reference to all aspects of
E.
thymifolia
and was arranged chronologically. Complete information of the plant has been collected from the various books and journals since the last 32 years, internet databases, etc., were searched. Compiled data reflects the safety and therapeutic efficacy of the plant. This will be helpful for researchers to focus on the priority areas of research yet to be explored and in scientific use of the plant for its wide variety of traditional therapeutic claims and also as to find out new chemical entities responsible for its claimed traditional activities.
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11,411
491
11
ARTICLES
Medico - botanical study of Yercaud hills in the eastern Ghats of Tamil Nadu, India
M Parthipan, V Aravindhan, A Rajendran
April-June 2011, 30(4):104-109
The study reports medicinal plant survey was conceded in Yercaud hills ranges of Eastern Ghats, Tamil Nadu, India. The study primarily based on field surveys conducted throughout the hills, where dwellers provided information on plant species used as medicine, plant parts used to prepare the remedies and ailments to which the remedies were prescribed. The study resulted about 48- plant species belonging to 45- genera and 29- families of medicinal plants related to folk medicine used by the local people. Among them the most common plants viz., Asparagus racemosus Willd., Cissus quadrangularis L., Gymnema sylvestre R. Br., Hemidesmus indicus (L.) R. Br., Justisia adhatoda L., Ocimum sanctum L., Phyllanthes amarus Schum. & Thonn., Piper nigrum L., Solanum nigrum L., Tinospora cordifolia (Thunb.) Miers, Tridax procumbens L. and Zingiber officinale Roscoe which are used in their daily life to cure various ailments.
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Nomenclature of
Anukta Dravya
Ganji Kusuma, VK Joshi
April-June 2010, 29(4):17-23
PMID
:22557363
Field survey was conducted in rural areas of Varanasi district of Uttar Pradesh including Ramnagar, Manduadih and surrounding areas to identify and collect information on undocumented medicinal plants (Anukta Dravya) by direct interaction with folklore people through field survey and indirect means by means of comprehensive survey of available literature. Local names of undocumented medicinal plants along with other relevant information were collected, after recording local names of medicinal plants, their botanical identification was done by comprehensive survey of literature, and the plants were identified according to Bentham & Hooker's system of classification using local floristic works. Expert opinion of plant taxonomists was also sought for cross checking and confirmation on identity. The freshly collected specimens were photographed for visual identification of the species. After identification, nomenclature of 10 Anukta Dravya was done as per the criteria of nomenclature mentioned in Nighantus.
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10,481
480
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ORIGINAL ARTICLES
Experimental evaluation of
Hiṅgvādi Ghṛta
in behavioral despair using animal models
Poonam Ashish Gupte, Jayshree Dawane, Asmita Ashish Wele
October-December 2016, 36(2):84-89
DOI
:10.4103/asl.ASL_78_16
PMID
:28446829
Context:
Depression, a sustained mood disorder caused by selective diminution of specialized cells in brain is increasing at an alarming rate. It will be the second largest morbid illness by next decade and is the leading cause of suicidal deaths. The available antidepressant medications benefit only a third of its recipients and have many side effects. Hence, it is imperative to search in Ayurveda for leads.
Aim:
To evaluate Anti- depressant activity of
Hiṅgvādi Ghṛta in vivo
.
Settings and Design:
Comparative preclinical study.
Materials and Methods:
Hiṅgvādi Ghṛta
(HG) was prepared using standard operating procedure, physicochemically analyzed and assessed. Tail Suspension Test (TST) model with Swiss albino mice and Forced Swim Test (FST) model with Wistar albino rats were used to assess anti-depressant activity. Imipramine hydrochloride in dose of 15 mg/kg for TST and 10 mg/kg for FST, was the standard drug and
Ghee
as vehicle control in dose of 0.1g/20g for TST and 0.72g/200g for FST orally.
Hiṅgvādi Ghṛta
in doses of 0.05g/20g (x/2), 0.1g/20g (x) and 0.2 g/20g (2x) for TST and 0.36g/200g (x/2), 0.72g/200g (x) and 1.44g/200g (2x) for FST was administered to 3 test groups for 21 days orally except Plain control group which received only distilled water. Duration of immobility in seconds for TST and number of rotations for FST were noted for assessment.
Statistical Analysis Used:
One way ANOVA followed by Dunnets test and Paired
t
test.
Results:
HG was significantly effective at dose of 0.1gm/20gm for TST (
P
= 0.0037;
P
< 0.01) and 0.72g/200g for FST (
P
= 0.0055,
P
< 0.01) comparable to Imipramine hydrochloride.
Conclusions:
HG displayed potent anti depressant activity comparable to standard drug Imipramine Hydrochloride.
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101
2
BOOK REVIEW
Textbook of "Knowledge Traditions and Practices of India"
Kapil Kapoor, Michel Danino
July-September 2012, 32(1):59-60
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9,549
660
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REVIEW ARTICLE
Antidiabetic effects of artemisia species: A systematic review
Nikodimos Eshetu Dabe, Adane Teshome Kefale
April-June 2017, 36(4):175-181
DOI
:10.4103/0257-7941.219369
PMID
:29269967
Background:
Over the last century, human life style and food habits have drastically changed which lead to various chronic diseases. Diabetes mellitus is one such disease which is causing serious problems to human health. Allopathic drugs are not much effective in handling the disease and its complications. Hence focus has been turned towards the traditional system of medicine. Medicinal plants play an important role in the management of diabetes mellitus.
Methods:
Experimental studies conducted on species of Artemisia on diabetic animal models and human published since the year 2000 until April, 2017 were reviewed. Each article was critically appraised by two independent reviewers for their methodological quality using the JBIMAStARI tool.
Result:
A total of 14 studies were included in this review and the blood glucose data obtained from these critically reviewed studies clearly showed that both the aqueous and alcoholic extracts of species of Artemisia produced significant hypoglycemic effects in alloxan, Streptozotocin and high fat diet induced diabetic animals and diabetic humans with different mechanisms of action as compared to standard antidiabetic medications.
Discussion and Conclusion:
The antidiabetic effect of single or multiple doses of aqueous and alcoholic extracts of Artemisia species was due to the active compounds of these plants and they all are effective in lessening the blood glucose level in all of those experimental studies. Despite the presence of known antidiabetic medicines in the pharmaceutical market, therapeutic remedies from these medicinal plants have been utilized with success to treat this disorder and its complications with a relatively less side effects.
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9,220
398
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CASE REPORTS
Integration of ayurveda and conventional medicine for chronic wound healing
Anupama Kizhakkeveettil, Christie Smirl, Jayagopal Parla
January-March 2018, 37(3):168-172
DOI
:10.4103/asl.ASL_108_18
Background:
Chronic wounds affect around 2.4 – 4.5 million patients in the United States. The burden of wound management is growing rapidly.
Objective:
Management of chronic wounds with integrated conventional medicine and Ayurveda treatment.
Clinical Features:
A 52-year-old female patient, presented with non-healing chronic wound on the right leg with pain persisting for 5 years. Initial measurement of the wound was 48 cm length × 13 cm width × 0.4 cm depth.
Intervention and Outcomes:
Wound depth was measured during different stages of healing along with photographic images. Patient was given Ciprofloxacin 500mg twice daily for 10 days, compression leg wraps and diuretics along with washing of the wound with Triphala decoction daily and application of wound dressing with Turmeric powder, neem bark powder and Medihoney daily were done. Marma therapy was performed once a week. Patient was also suggested kapha pacifying diet and lifestyle.
Results:
The wound was completely healed with normal skin coloration by the sixth week.
Conclusions:
This case study discusses the use of integration of ayurvedic herbs with conventional medicine for the management of wound healing. Interventional studies should be conducted to better understand the effectiveness of this integrative approach for the treatment of chronic wounds.
[ABSTRACT]
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9,324
217
2
REVIEW ARTICLE
Śodhana: An Ayurvedic process for detoxification and modification of therapeutic activities of poisonous medicinal plants
Santosh Kumar Maurya, Ankit Seth, Damiki Laloo, Narendra Kumar Singh, Dev Nath Singh Gautam, Anil Kumar Singh
April-June 2015, 34(4):188-197
DOI
:10.4103/0257-7941.160862
PMID
:26283803
Ayurveda involves the use of drugs obtained from plants, animals, and mineral origin. All the three sources of drugs can be divided under poisonous and nonpoisonous category. There are various crude drugs, which generally possess unwanted impurities and toxic substances, which can lead to harmful health problems. Many authors have reported that not all medicinal plants are safe to use since they can bear many toxic and harmful phytoconstituents in them.
Śodhana
(detoxification/purification) is the process, which involves the conversion of any poisonous drug into beneficial, nonpoisonous/nontoxic ones.
Vatsanābha
(
Aconitum
species),
Semecarpus anacardium, Strychnos nux-vomica, Acorus calamus, Abrus precatorius
etc., are some of the interesting examples of toxic plants, which are still used in the Indian system of medicine.
Aconite
, bhilawanols, strychnine, β-asarone, abrin are some of the toxic components present in these plants and are relatively toxic in nature.
Śodhana
process involves the purification as well as reduction in the levels of toxic principles which sometimes results in an enhanced therapeutic efficacy. The present review is designed to extensively discuss and understand the scientific basis of the alternative use of toxic plants as a medicine after their purification process.
[ABSTRACT]
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8,838
634
23
Significance of gingers (Zingiberaceae) in Indian System of Medicine - Ayurveda: An overview
Konickal Mambetta Prabhu Kumar, Gopinathan Ramanikutty Asish, Mamiyil Sabu, Indira Balachandran
April-June 2013, 32(4):253-261
DOI
:10.4103/0257-7941.131989
PMID
:24991077
Background:
Family Zingiberaceae consists of the large number of medicinal plants and is well-known for its use in ethnomedicine and play a major role in Indian System of Medicine, Ayurveda.
Objective:
The aim of this study is the documentation of Zingiberaceous plants used in Ayurveda, adding information to the systematics, vernacular names and chemistry with experimental data.
Materials and Methods:
The live plants were collected from wild and successfully conserved at Herbal Garden of Arya Vaidya Sala, Kottakkal. The experimental data of each species has been collected from the various sources. The photographs were taken and all relevant data documented.
Results
and
Conclusion:
A total of 13 species belonging to 7 genera of Zingiberaceae were documented. The work will be useful to students and researchers as it provides an easy access to Zingiberaceous plants used in Ayurveda.
[ABSTRACT]
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8,853
454
22
SHORT COMMUNICATIONS
Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study
Sampath K Vemula, Mukesh B Chawada, Kapil S Thakur, Mahesh K Vahalia
October-December 2012, 32(2):112-115
DOI
:10.4103/0257-7941.118551
PMID
:24167338
Context:
Amlapitta Mishran suspension is a poly herbal ayurvedic formulation, which has been traditionally used for acidity and gastric ulcers.
Aim:
The aim of this study is to evaluate the antiulcer activity of Amlapitta Mishran on non-steroidal anti-inflammatory drugs (NSAID's) -induced ulcers in the rat model.
Subjects and Methods:
The antiulcer activity of Amlapitta Mishran was investigated on indomethacin (100 mg/kg) NSAID's induced ulcers in rats. Effect of two different doses of Amlapitta Mishran was studied by calculating the total number of ulcers, ulcer index and percentage inhibition.
Statistical Analysis Used:
Data was analyzed by the Student's
t-
test (
P
< 0.05).
Results:
Amlapitta Mishran treated rats have shown significant (
P
< 0.0001) decrease in the total number of ulcers and ulcer index and significant increase in % inhibition of ulcers as compared with positive control group.
Conclusion:
The results indicate that Amlapitta Mishran has showed a dose dependent antiulcer activity in experimental animals and confirms ayurvedic use of Amlapitta Mishran in gastric ulcers.
[ABSTRACT]
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9,076
204
6
BOOK REVIEW
Angamardhana: A treatise on massage techniques of ancient India
BS Praveen
January-March 2017, 36(3):170-171
DOI
:10.4103/asl.ASL_162_16
[FULL TEXT]
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8,778
473
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ORIGINAL ARTICLES
Detailed pharmacognostical and analytical profile of telosma pallida (l.) kurz. (leaf): A folklore medicinal plant of Gujarat State
Riddhi Dineshkumar Kanakhara, Harisha Channappa Rudrappa, Vinay Janardan Shukla, Rabinarayan Acharya
January-March 2018, 37(3):120-126
DOI
:10.4103/asl.ASL_97_17
Background:
Telosma pallida
(L.) Kurz., is one of the traditional medicinal plants from Asclepiadaceae family. It is abundantly available in Gujarat, India during monsoon. It is a slender and deciduous climber used traditionally in the treatment of various diseases such as cough, cold, skin diseases etc.,
Aims:
To study the leaves of
Telosma pallida
(L.) Kurz. for detailed Pharmacognostic characters and Analytical Profile.
Materials and Methods:
In this work pharmacognostic, preliminary phytochemical screening, fluorescence analysis, and HPTLC profile of leaves were determined following standard procedures.
Results:
The leaves are simple, entire, opposite, cordate in shape, the upper surface is dark green and lower surface is light green in colour. The Transverse section of a leaf through petiole shows the presence of uniseriate multicellular warty trichomes and laticifer cells at the adjacent side of the phloem. Surface study shows paracytic and anomocytic type of stomata. Preliminary physicochemical analysis shows water soluble extractive value as 28.44 ± 2.89% w/w and alcohol soluble extractive value as 14.60 ± 0.79% w/w. Preliminary phytochemical analysis of extracts shows the presence of glycosides, alkaloids, carbohydrates, proteins, amino acids and flavonoids.
Conclusion:
The information obtained from this research work may be useful to establish the botanical as well as analytical standards for the leaves of
T. pallida
.
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Quality control parameters for
Tamra
(copper)
Bhasma
Chandrashekhar Yuvaraj Jagtap, Pradeepkumar Prajapati, Biswajyoti Patgiri, Vinay J Shukla
April-June 2012, 31(4):164-170
DOI
:10.4103/0257-7941.107348
PMID
:23661863
Background:
Metallic
Bhasmas
are highly valued and have their own importance in Ayurvedic formulations. To testify the
Bhasmas
various parameters have been told in
Rasashastra
classics.
Tamra Bhasma
(TB) with its different properties is used in the treatment of various diseases is quiet famous among the Ayurvedic physicians (
Vaidyas
).
Objectives:
The present study was carried out to set up the quality control parameters for the TB by making the use of classical tests along with advanced analytical tools.
Settings and Design:
Copper wire taken for the preparation of
Bhasma
was first analyzed for its copper content and then subjected to
Shodhana, Marana
and
Amrutikarana
procedures as per the classical references. Final product complied with all the classical parameters like
Rekhapurnatwa
, Varitaratwa etc.
Materials and Methods:
After complying with these tests TB was analyzed by advanced analytical techniques like particle size distribution (PSD) analysis, scanning electron microscopy (SEM), and inductive coupled plasma spectrometry (ICP).
Results:
PSD analysis of TB showed volumetric mean diameter of 28.70 μm, 50% of the material was below 18.40 μm size. Particle size less than 2μm were seen in SEM. 56.24 wt % of copper and 23.06 wt % of sulphur was found in ICP-AES. Heavy metals like cadmium, selenium were not detected while others like arsenic, lead and mercury were present in traces.
Conclusions:
These observations could be specified as the quality control parameters conforming to all the classical tests under the
Bhasma Pariksha
.
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8,132
675
3
CASE REPORTS
An approach to avascular necrosis by
Saghṛta kṣīrabasti
Sreelaksmi Chaganti, Rajashekhar V Sanipeti, Suma S. S Joshi
July-September 2013, 33(1):45-48
DOI
:10.4103/0257-7941.134602
PMID
:25161330
A 62-year-old, male patient radiologically diagnosed as a case of avascular necrosis of femur head with grade 4, presented the following chief complaints. Pain in the left hip joint radiating to thigh (anterior part), of grade '9' on “visual analog scale (VAS)” associated with swelling in bilateral feet and decreased range of movements in the hip joint. This presentation was correlated with
Asthi-majjagata v
ā
ta (musculo-skeletal disorder)
and treated accordingly. Initially, patient had been administered
d
ī
pana
and
p
ā
cana
followed by
nityavirecana
(therapeutic purgation). Further
Saghrita k
ṣ
ī
rabasti
(medicated enema prepared with milk and ghee) was administered in
kal
ā
basti
schedule (16 in number). This resulted with relief of pain to grade “3” on “VAS” and complete resolution of pedal edema and improvement in range of movement of hip joint.
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8,480
292
1
A case report on ayurvedic management of acute renal colic
Amit Nakanekar, Pallavi Thote, Niharika Palan, Prashant Deshmukh, Jayant Gulhane, Amrut Salunke
January-March 2018, 37(3):162-167
DOI
:10.4103/asl.ASL_7_18
Background:
Acute renal calculus is a common recurrent and emergency condition with an annual incidence of one to two cases per 1000. Lifetime risk of its recurrence is 10–20% in men and 3–5% in women. It is an important cause of acute renal failure. About 12% of the population of India is reported to have urinary stones. Acute attacks are managed by analgesics, antispasmodics and use of Non-steroidal anti-inflammatory drugs (NSAIDs). In this case report we report an acute renal colic case managed by Ayurveda treatment without using any modern analgesics.
Case Summary:
A 34 year old male patient presented with severe pain in abdomen radiating from lower back to pubic symphysis, vomiting and nausea. Diagnosis of ureteric stone was confirmed by Ultrasonography (USG) of abdomen. We gave him local
snehana
(~local massage with sesame oil),
nāḍi svedana
(~fomentation),
basti
(~medicated enema) and oral Ayurveda medicines. Reduction in acute pain was achieved in three hours. Painless removal of stone was also achieved in seven days.
Conclusion:
This case study provides an example of successful management of acute renal colic with Ayurveda treatment alone and without using any modern analgesics. This case study also gives leads for the experiments on role of gut in the management of pain. Clinical trials on
Ayurveda
management of acute renal colic are warranted.
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8,415
275
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ARTICLES
Biopotency of
Acalypha indica
Linn on Membrane Bound ATPases and Marker Enzymes urolithic Rats
M Sathya, R Kokilavani, KS Ananta Teepa, A Balakrishnan
July-September 2011, 31(1):3-9
PMID
:22736883
The ethanolic extract of
Acalypha indica
was tested for its biopotency on membrane bound enzymes and marker enzymes in urolithiasis in male wistar albino rats. Calcium oxalate urolithiasis was induced by 0.75% ethylene glycol in drinking water for 30 days. There was a significant decrease in membrane bound enzymes such as Ca
2+
ATPase, Mg
2+
ATPase, Na
+
K
+
ATPase and marker enzymes Aspartate Transaminase (AST), Alanine Transaminase (ALT), Acid phosphatase (ACP) and Alkaline Phosphatase (ALP) in liver and kidney. The AST, ALT, ACP and ALP were increased in serum and urine of rats. Therapeutic treatment with plant extract (200mg/kg b.wt.dose
-1
day
-1
oral
-1
) has significantly ameliorated to near normalcy in the curative group. These results of the present study concluded that A. indica can play an important role in the prevention of disorders associated with kidney stone formation .
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8,308
376
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Online since 25 September, 2011