The hepatoprotective effect of Annona muricata and Polyalthia cerasoides (Annonaceae) were monitored by estimating the serum transaminases (SGOT and SGPT), serum alkaline phosphatase (SALP), liver and brain lipid peroxidation (LOP) and their total protein content. Both drugs at a dose of 100 μg/kg significantly prevented the increase in serum transaminases, SALP, liver and brain LOP and decrease in liver and brain total protein content following carbontetrachloride (CCl) induced hepatoxicity in albino rats.

High performance thin layer chromatographic finger print parameters had been developed for the siddha medicine 'Maka Vallati Ilekiyam' to fix standards.

The description of metabolic processes, operating at various levels insider the body, has been essentially covered in Ayurveda under thirteen types of Agnis and their functions at different levels, which are often compared with the enzymes and biochemical which take part in biological and / or biophysical transformations and reactions. When these Agnis, at different levels, get disordered they lead to the production of certain undesired elements or byproducts in the system, which are called as 'Ama' in ayurveda and are considered as very important morbid factor responsible for causation of a variety of diseases and playing key role in genesis of most of the diseases. The present article attempts to correlate the most recent concept of today's medicine i.e., Free Radical concept with that of the concept of Agni and Ama, described in Ayurveda and thereby opens newer vistas of search for remedies from Ayurvedic research, which may be helpful in the prevention and care of Free Radical Mediated Diseases.

Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001). Sperm motility and density were significantly reduced. Reduced testicular and accessory organ protein, sialic acid and vesicular fructose content manifested arrest of spermatogenesis and depletion of androgen level.

Bryonia epigaea (cucurbitaceae) has been evaluated on various inflammatory models in rats in our laboratory. Ana anti-inflammatory drug(s) irrespective of its potency may not be devoid of undesirable effects on biochemical and hematological parameters. Alcoholic extract of Bryonia epigaaea (BE-Extract) at the dose of 50 mg/kg body weight, was administered to rats. Hepatotxic and nephrotoxic effects of BE-Extract were studies by measuring cholesterol, urea, uric acid, SGOT, SGPT and glucose levels in blood. Effects of BE-Extract on RBC count, WBC count, platelet count, hemoglobin content, clotting and bleeding time were also studied.

The present communication deals with medicinal uses of Andrographis paniculata Nees by the tribals in Tamilnadu. Hitherto unreported uses are presented based on the Malayli tribals of Tamilnadu.

The present paper deals with the ethno-medico-botany of Chenchus of Mahaboobnagar district, Andhra Pradesh. About fourty four plants are enumerated with knowledge of the tribals for their medicinal uses in curing different diseases and ailments.

A simple, rapid and economical procedure for estimation of Embelin by UV Spectrophotometer in Embelia ribes was developed and is described. The method is based on the identification of Embelin by TLC and on the ultra violet absorbance maxima in chloroform at 285 nm. A value of 4.80% w/w of Embelia was found in test simple.

'Lingha chendooram' number 1 is a single drug useful in Siddha system of medicine. This is prepared from Cinnabar, the chief ore of mercury. The standardization is carried out with respect to the presence of Mercury and Sulphur in the drug.

Thuja occidentalis Linn. (Family cupressaceae), commonly known as American Arbore Vitae, is an evergreen tree and native of North America. Leaves & twigs, which contains essential oil, condylomatous growth, spongy tumours, warts, ill effects of vaccination etc. Twigs fan-shaped; leaves ovate, obtuse, having resin ducts & parenchymatous mesophyll; stem shows resins ducts in parenchymatous cortex and alternate bands of phloem parenchyma & phloem fibres. TLC of alcoholic extract in chloroform: Methanol (9:1) shows 8 spots under UV light, and UV absorbance shows peak at 260nm.

Morphological, anatomical, quantitative microscopy powder microscopy, physical constant preliminary phytochemical analysis and fluorescence analysis of the leaves of Aglaia roxburghiana Var. Beddome were carried out.

Different strength of alcohol 40.50,60,70,80,90 per cent (v/v) and absolute were utilized for the preparation of tincture of azadirachta Indica A. Juss leaves by maceration for 7, 14,21 days. 60 per cent tincture produced after 21 says of maceration showed a maximum solid content of 1.425 per cent (v/v) and sowed pH 3.15. This tincture was characterized by studying is various physico-chmicla properties along wit its thin-layer chromatographic characteristics.

The crude native oil and purified seed oil of Mesua ferrea were studied for their effect on isolated rat il eum by taking standard spasmodic and antispasmodic drugs. The crude oil of seed showed significant antispasmodic activity but purified oil was devoid of any antispasmodic activity.

Transdermal diffusion studies of a polyherbal ointment were carried out in vito using franz- Diffusion cell and microbial one inhibition diameter as drug release monitoring parameters. Out of the three ointment base prepared, (Hydrocarbon Base (HB), surfactant Base (SB), Surfactant Base + (Penetration Enhancer (10 % DMSO) SBPE), we observed that SBPE possesses maximum drug release capacity, as indicated by simultaneous high performance liquid chromatograph (HPLC) and microbial one inhibition monitoring studies. Clinical observations showed at SBPE was effective in cases like infected wounds, scratches and abrasions, infected scabies, pyoderma and furunculosis. The overall cure rate s 79.3% with the antimicro-bial ointmtmtent.