Year : 2012 | Volume
: 32 | Issue : 2 | Page : 112--115
Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study
Sampath K Vemula, Mukesh B Chawada, Kapil S Thakur, Mahesh K Vahalia
Biomedical Services, Shree Dhootapapeshwar Ayurvedic Research Foundation, Navi Mumbai, Maharashtra, India
Context: Amlapitta Mishran suspension is a poly herbal ayurvedic formulation, which has been traditionally used for acidity and gastric ulcers.
Aim: The aim of this study is to evaluate the antiulcer activity of Amlapitta Mishran on non-steroidal anti-inflammatory drugs (NSAID«SQ»s) -induced ulcers in the rat model.
Subjects and Methods: The antiulcer activity of Amlapitta Mishran was investigated on indomethacin (100 mg/kg) NSAID«SQ»s induced ulcers in rats. Effect of two different doses of Amlapitta Mishran was studied by calculating the total number of ulcers, ulcer index and percentage inhibition.
Statistical Analysis Used: Data was analyzed by the Student«SQ»s t-test (P < 0.05).
Results: Amlapitta Mishran treated rats have shown significant
(P < 0.0001) decrease in the total number of ulcers and ulcer index and significant increase in % inhibition of ulcers as compared with positive control group.
Conclusion: The results indicate that Amlapitta Mishran has showed a dose dependent antiulcer activity in experimental animals and confirms ayurvedic use of Amlapitta Mishran in gastric ulcers.
Mahesh K Vahalia
Shree Dhootapapeshwar Ayurvedic Research Foundation, Veer Savarkar Chowk, Panvel, Navi Mumbai - 410 206, Maharashtra
|How to cite this article:|
Vemula SK, Chawada MB, Thakur KS, Vahalia MK. Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study.Ancient Sci Life 2012;32:112-115
|How to cite this URL:|
Vemula SK, Chawada MB, Thakur KS, Vahalia MK. Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study. Ancient Sci Life [serial online] 2012 [cited 2023 Mar 23 ];32:112-115
Available from: https://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2012;volume=32;issue=2;spage=112;epage=115;aulast=Vemula;type=0