Ancient Science of Life

ARTICLE
Year
: 2007  |  Volume : 27  |  Issue : 1  |  Page : 14--18

Antipyretic activity of Radix paeoniae


Sapna Motwani, Neelesh Malviya, RK Goel, KR Dutt 
 B.R. Nahata College of Pharmacy, Mandsaur (M.P.), India

Correspondence Address:
Sapna Motwani
B.R. Nahata College of Pharmacy, Mandsaur (M.P.)
India

The acetone extracts of Radix paeoniae  (Paeonaceae) root (100 and 200 mg/kg orally) were tested in brewer«SQ»s yeast-induced pyrexia in rats to assess their antipyretic activity. The pyrexia in rats was reduced significantly (P < 0.05) compared to that of control. These results indicate that the extracts possess antipyretic properties. The root extract showed significant reduction in normal body temperature and yeast-provoked elevated temperature comparable to that of standard antipyretic drug paracetamol. The antipyretic effect was started at 1h and extended for at least 4h after the drug administration.


How to cite this article:
Motwani S, Malviya N, Goel R K, Dutt K R. Antipyretic activity of Radix paeoniae.Ancient Sci Life 2007;27:14-18


How to cite this URL:
Motwani S, Malviya N, Goel R K, Dutt K R. Antipyretic activity of Radix paeoniae. Ancient Sci Life [serial online] 2007 [cited 2022 Jun 25 ];27:14-18
Available from: https://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2007;volume=27;issue=1;spage=14;epage=18;aulast=Motwani;type=0