Ancient Science of Life

ARTICLE
Year
: 2006  |  Volume : 26  |  Issue : 1  |  Page : 73--77

Amelioration of mercuric chloride induced nephrotoxicity and oxidative stress by Garlic extract


N Abirami, R Jagadeeswari 
 PG and Research Department of Biochesmistry, Dr. N.G.P. Arts and Science College, Kovai Medical Centre for Research and Education Trust, Coimbatore -641 035, Tamilnadu, India, India

Correspondence Address:
N Abirami
PG and Research Department of Biochesmistry, Dr. N.G.P. Arts and Science College, Kovai Medical Centre for Research and Education Trust, Coimbatore -641 035, Tamilnadu, India
India

Effect of Garlic against mercuric chloride induced toxicity in albino rats was studied. Oral administration of mercuric chloride (100mg/kg/p.o) for 30 days resulted in significant increase in LPO Basal level and LPO FeSO4  induced and significant decrease in GSH (Glutathione) and Vit C as compared to the normal and control group. Simultaneous administration of Garlic along with Mercuric chloride, produced a pronounced neproprotective effect against mercuric chloride induced toxicity in rats by restoring the normal levels of biochemical parameters.


How to cite this article:
Abirami N, Jagadeeswari R. Amelioration of mercuric chloride induced nephrotoxicity and oxidative stress by Garlic extract.Ancient Sci Life 2006;26:73-77


How to cite this URL:
Abirami N, Jagadeeswari R. Amelioration of mercuric chloride induced nephrotoxicity and oxidative stress by Garlic extract. Ancient Sci Life [serial online] 2006 [cited 2023 Jan 27 ];26:73-77
Available from: https://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2006;volume=26;issue=1;spage=73;epage=77;aulast=Abirami;type=0