Ancient Science of Life

ARTICLE
Year
: 2000  |  Volume : 20  |  Issue : 1  |  Page : 6--10

Prevention of toxic effects of mercuric chloride on some male accessory organs in mice with a Multiherbal drug DQSpemanDQ


HS Rathore 
 Cell Biology Unit, School of Studies in Zoology, Vikram University, Ujjain 456010 (M.P), India

Correspondence Address:
H S Rathore
Cell Biology Unit, School of Studies in Zoology, Vikram University, Ujjain 456010 (M.P)
India

Adult Swiss albino male mice exposed to mercuric chloride via drinking water at 5 μg/ml for 100 days revealed significant reduction in the wet weight and severe histopathological changes in male accessory organs, poor level of serum testosterone and infertility. These effects were reduced remarkable and fertility was restored when drug (12.50 mg/mouse/day orally) was administered during mercury exposure for 100days or after Hg-exposure for next 60 days (Post therapy). Natural recovery after mercury exposure for 60 days remind ineffective. Probable action of herbal drug based on the presence of the active principles of constituents (i.e Orchis mascula, Mucuna pruriens, parmelia perlata, Argyreia speciosa, Tribulus terristris, Leptadenia reticulate, Lactuca scariola and Hygrophila spinosa) is discussed in detail.


How to cite this article:
Rathore H S. Prevention of toxic effects of mercuric chloride on some male accessory organs in mice with a Multiherbal drug "Speman".Ancient Sci Life 2000;20:6-10


How to cite this URL:
Rathore H S. Prevention of toxic effects of mercuric chloride on some male accessory organs in mice with a Multiherbal drug "Speman". Ancient Sci Life [serial online] 2000 [cited 2022 Jun 25 ];20:6-10
Available from: https://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2000;volume=20;issue=1;spage=6;epage=10;aulast=Rathore;type=0