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Year : 2016  |  Volume : 35  |  Issue : 3  |  Page : 183

Efficacy of herbomineral compounds and Pathya in the management of Yakṛt Roga

Professional Medical Writer, Airoli, Navi Mumbai, Maharashtra, India

Date of Web Publication8-Apr-2016

Correspondence Address:
Pravin Murgeppa Bolshete
Professional Medical Writer, Amey CHS, Sector - 15, Airoli, Navi Mumbai, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0257-7941.179863

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How to cite this article:
Bolshete PM. Efficacy of herbomineral compounds and Pathya in the management of Yakṛt Roga. Ancient Sci Life 2016;35:183

How to cite this URL:
Bolshete PM. Efficacy of herbomineral compounds and Pathya in the management of Yakṛt Roga. Ancient Sci Life [serial online] 2016 [cited 2023 Mar 30];35:183. Available from: https://www.ancientscienceoflife.org/text.asp?2016/35/3/183/179863


Recently I read an article by Singhal et al.[1] with great interest and have following comments. Authors conclude that “Pathya (Ayurvedic dietary regime and physical exercise) alone has not been found sufficient to treat this syndrome. Instead, a combination of herbomineral drugs (Ārogyavardhinī vaṃi and Triphalā Guggulu) and pathya/apathya have resulted in significant improvement in liver functions and body mass index (BMI) of non-alcoholic fatty liver disease (NAFLD) patients”. However, the overall results are difficult to conclude. For biochemical parameters [Table 5][1] P values were significant for all the parameters (before versus after treatment) in both groups, except for fasting blood sugar. Though, there are small numerical differences in biochemical parameters and some improvement seen in clinical symptoms, the overall conclusion of group A performing better than group B could be difficult, at least based on this open-label study with small sample size.{Table 5}

Authors report this study as retrospective study; however, the methods employed clearly demonstrate that the study is prospective in nature. It will be of interest to know if any ethics committee reviewed and approved the study protocol? Did the patients and their relatives (if applicable) provide written informed consent? How the sample size was calculated? It would have been better if the baseline demographics had been shown for both groups for better comparison, including history of previous and concomitant medications and results stratified by grades.

The 'NAFLD activity score' a standard outcome measure for NAFLD studies was also not included in this study.

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Conflicts of interest

Author is an employee of Tata Consultancy Services, Mumbai, however the views presented in this letter are of the author and not necessarily of his employer.

  References Top

Singhal P, Nesari T, Gupta GS. Efficacy of herbomineral compounds and pathya (Ayurvedic dietary regime and physical exercise) in the management of Yakrt Roga (Non-alcoholic fatty liver disease). Anc Sci Life 2015;34:216-22.  Back to cited text no. 1


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