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Year : 2012  |  Volume : 32  |  Issue : 5  |  Page : 77

PA01.27. Standardization of ayurvedic formulation 'eladi vati'

1 Faculty of Pharmacy, VNS Group of Institutions, Bhopal, India
2 Rajeev Gandhi Prodyogiki Mahavidyalaya, College of Pharmacy, Bhopal, India
3 Peoples Institute of Pharmacy and Research, Bhopal, India
4 Barkatullah University, Department of Pharmacy, Bhopal, India

Correspondence Address:
Ashish Singhai
Faculty of Pharmacy, VNS Group of Institutions, Bhopal
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Source of Support: None, Conflict of Interest: None

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Purpose: Contamination, deterioration and variation in composition problem of herbal medicines can be resolved by developing physico chemical fingerprints for the standardization of the drugs and comparing them with the reference authentic drugs, variation between preparations from different companies and by evaluating batch-to-batch changes during long term storage. Method: In present context we had standardized the ayurvedic preparation Eladi vati by using chemical markers. This vati and individual herbs had been evaluated for various physicochemical parameters, in process evaluation parameters, TLC (as identification of active principles), quantitative determination of marker compounds by HPLC method, determination of microbial contamination and toxic heavy metals by Atomic Absorption Spectrophotometer. The piperine, gallic acid and glycyrrhizic acid were quantitatively determined. Result: The results obtained with individual herbs had been compared with standards and results obtained with formulation had been compared with the other similar vati formulations available in the market. The results are almost alike in the Piperine, Glycyrrhizic acid and Gallic acid content. The concentration of heavy metals and microbial contamination were found under limit in ppm and colony forming units per gm respectively. Conclusion: The method can be suggested for effective quality control of herbal products and will establish standardization parameters for identification, quantification and purity determinations.

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