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Year : 2012  |  Volume : 32  |  Issue : 5  |  Page : 108

PA01.58. Role of laghu malini vasanta rasa in management of madhumeha, type 2 diabetes mellitus

Department of Rasa Shastra and Bhaishajya Kalpana, IPGT & RA. Gujarat Ayurved University, India

Correspondence Address:
Manisha B Walunj
Department of Rasa Shastra and Bhaishajya Kalpana, IPGT & RA. Gujarat Ayurved University
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Source of Support: None, Conflict of Interest: None

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Purpose: Laghu Malini Vasanta Rasa is a Vasanta Malati Kalpa with Rasaka and Maricha as main ingredients, chiefly acting on Dhatvagni with Brimhana effect. It had been quoted by 30 texts and mentioned under Jeerna Jwaradhikara. None of text had mentioned it for Madhumeha. Madhumeha is chronic disorder where Dhatvagnimandya leads to diminution of Prasada Dhatu resulting in Vataprakopa .Type 2 Diabetes Mellitus is more prevalent among other types 62.4 million in 2011.Long termed hyperglycemia in Type 2 DM results in decreased quality of life 2.263 million disability adjusted life years in India during 2004. Through present study attempt was made to evaluate efficacy of formulation (AFI part I 20:36) in Madhumeha as anti-hyperglycaemic activity of ingredients of Laghu Malini Vasanta Rasa has been recognized. Method: Open trial (CTRI registration no. CTRI/2011/11/00211) Inclusion criteria- Age group 30 60 yrs, Patients with cardinal symptoms of Madhumeha Exclusion criteria-Age group < 30 >60yrs, Accelerated HTN, Pregnant, Lactating mother, CNS complication Diagnostic criteria- Subjective criteria: Classical signs & symptoms of Madhumeha, Objective criteria: FBS(fasting blood sugar)> 126 mg/dl OR PPBSL(postprandial blood sugar level)> 200 mg/dl, Total Reg.patient- 33; completed-30; Dropped out-3, Posology with duration of treatment: 250mg tablet BD 30 min. before meal with lukewarm water for 8 weeks. Criteria for assessment: Relief in symptoms by Wilcoxson signed rank method. Unpaired t test for statistical analysis of objective parameters. Result: highly significant relief p < 0.001in symptoms Klama, Daurbalya and significant relief P<0.05in reducing urine sugar and PPBSL (postprandial blood sugar level). Conclusion: Laghu Malini Vasanta helped to improve quality of life in-patient of Madhumeha.

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