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Year : 2010  |  Volume : 29  |  Issue : 3  |  Page : 30-32

Effect of selected Antiasthmatic plant constituents against micro organism causing upper respiratory tract infection

1 Asst. Professor, Department of Pharmacognosy, JSS College of Pharmacy, Rocklands, Ootacamund, Tamil Nadu.-643 001, India
2 Department of Pharmacognosy, JSS College of Pharmacy Rocklands, Ootacamund, Tamil Nadu, India

Correspondence Address:
P Nilani
Asst. Professor, Department of Pharmacognosy, JSS College of Pharmacy, Rocklands, Ootacamund, Tamil Nadu.-643 001
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Source of Support: None, Conflict of Interest: None

PMID: 22557357

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Most exacerbations of asthma can be proven to be associated with bacterial infections and there is scientific evidence that frequent respiratory infections particularly bacterial infections provoke asthma attack. Considering these facts different plant extracts and phytoconstituents with proven anti asthmatic property had been selected for screening anti microbial activity in in-vitro models. In the present study, Coleus forskohlii Willd. extract (10% Forskolin), Piper Longum L. Extract (20% Piperine), Adathoda vasica Nees. extract (30% Vasicinone), Curcuma longa L. extract (60% Curcumin) were screened for the antibacterial activity against human pathogens causing upper respiratory infection namely Haemophilus influenzae , Streptococcus pneumoniae , Streptococcus pyrogene and Staphylococcus aureus, by taking Gentamycin, Optochin, Bacitracin and Amoxicillin as reference standards. Except for Adathoda vasica Nees. extract, all the other selected plant extracts exhibited a moderate activity antibacterial activity against selected strains.

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