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Year : 2008  |  Volume : 27  |  Issue : 3  |  Page : 36-40

Antitussive activity of ethanolic extract of Curcuma aromaticarhizomes on sulfur dioxide induced cough in mice

1 K.L.E.S College of Pharmacy, Vidyanagar, Hubli, India
2 Department of Microbiology, S.R.N.M.N College of Applied Sciences, Shimoga, India

Correspondence Address:
G D Marina
K.L.E.S College of Pharmacy, Vidyanagar, Hubli
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Source of Support: None, Conflict of Interest: None

PMID: 22557276

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Ethanolic extract of rhizomes of Curcuma aromatica  (Zingiberaceae) was investigated for its antitussive effect on Sulfur dioxide induced cough model in mice. The extract exhibited significant antitussive activity in a dose dependant manner. The activity was compared with the prototype antitussive agent codeine phosphate. The ethanolic extract at the dose of lOOmg. 200mg and 400mg/kg body weight, po, showed 68%, 74% and 79% of inhibition of cough with respect to control group.

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