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Year : 2003  |  Volume : 22  |  Issue : 4  |  Page : 146-151

Diuretic activity of Coleus Aromaticus benth on rats

1 Department of Pharmacology, University College of Medicine, Kolkata 700 020, India
2 J.B. Roy State Ayurvedic Medical College & Hospital, Kolkata 700 004, India

Correspondence Address:
T K Sur
Department of Pharmacology, University College of Medicine, Kolkata 700 020
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Source of Support: None, Conflict of Interest: None

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Water extract of the leaves of Coleus Aromaticus benth  was tested for its diuretic activity in male albino rats. The study was carried out on normal rats using furosemide as a standard reference drug. Rats were treated with furosemide (4 mg/kg. p.o) and Coleus aromaticus (0.5 g/kg and 1.0 g/kg, p/o). Urine was collected and its volume was recorded. Urinary levels of sodium, potassium and chloride were estimated. Treatment with Coleus aromaticus produced diuresis. The urine output and electrolytes concentration was significantly increased. Hence, it is suggested, Coleus aromaticus leaves has diuretic activity on rats.

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