| ARTICLE |
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| Year : 2002 | Volume
: 22
| Issue : 1 | Page : 9-12 |
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Purgative and anti-inflammatory activities of Cassia didymobotrya, Fresen
N Mahadevan, BG Upendra, T Subburaju, K Elango, B Suresh
Department of Pharmacognosy, J.S.S College of Pharmacy, Ooty, India
Correspondence Address:
N Mahadevan
Department of Pharmacognosy, J.S.S College of Pharmacy, Ooty
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Aqueous and ethanol extracts of cassia didymobotraya were investigated for
purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract
showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13. |
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