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Year : 2002  |  Volume : 22  |  Issue : 1  |  Page : 9-12

Purgative and anti-inflammatory activities of Cassia didymobotrya, Fresen

Department of Pharmacognosy, J.S.S College of Pharmacy, Ooty, India

Correspondence Address:
N Mahadevan
Department of Pharmacognosy, J.S.S College of Pharmacy, Ooty
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Source of Support: None, Conflict of Interest: None

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Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13.

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