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Year : 2002  |  Volume : 21  |  Issue : 4  |  Page : 256-259

Antiulcer activity of Aegle marmelos Linn

1 C.L. Baid Metha college of pharmacy, Channai, India
2 Adhiparasakthi College of Pharmacy, Melmaruvathur 603 319, India
3 Department of Biochemisry, University of Madras, Guindy Campus, Chennai 600 032, India

Correspondence Address:
J R Ilavarasan
C.L. Baid Metha college of pharmacy, Channai
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Source of Support: None, Conflict of Interest: None

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Aegle marmelos Linn is a common plant used to treat many disease Conditions in Indian traditional systems of medicine. The present study was undertaken to findout a scientific validation for the efficacy of Aegle marmelos against gastric ulcer. Aqueous extract of Aegle marmelos leaves was prepared and used for investigation. A daily does of 1 gm/kg body weight of the extract administered orally for 21 days. The volume of the gastricse cretion, ulcer lesion count, pepsin content, PH, total acidity, hexose and hexosamine content were estimated. The result indicated a significant reduction in the ulcer lesion count, volume of gastric juice and acidity and increase in pH and hexosamine after treatment with extract. However the pepsin and hexose content not significantly altered. Histopathological studies were conducted to support the antiulcer study.

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