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Year : 2001  |  Volume : 21  |  Issue : 2  |  Page : 99-110

Pharmacological properties of a protease from Ficus hispiad Linn

1 Department of Pharmaceutical Science, Dibrugarh University Dibrugarh-786 004, India
2 Department of Pharmaceutical Technology, Jadavpur University Calcutta 700 032, India

Correspondence Address:
D Chetia
Department of Pharmaceutical Science, Dibrugarh University Dibrugarh-786 004
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Source of Support: None, Conflict of Interest: None

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A sulphydryl plant protease present in the latex of Ficus hispida  Linn affects hatematological values in mice. The isolated protease was found to increase clotting time and erythrocyte sedimentation rate while haemoglobin conten, RBC count and WBC count were decreased in a dose dependent manner. Ointment containing 1.0% (w/w) hispidain in washable ointment base showed good wound healing property in mice. The protease also possesses mild anti inflammatory activity.

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