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ARTICLE
Year : 2001  |  Volume : 21  |  Issue : 1  |  Page : 12-15

Antihepatotoxic acticity of Coccinia indica


College of pharmacy, Sri Ramachandra Medical College & Research Institute, (Deemed university), Chennai-600 116, India

Correspondence Address:
V Gopalakrishnan
College of pharmacy, Sri Ramachandra Medical College & Research Institute, (Deemed university), Chennai-600 116
India
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Source of Support: None, Conflict of Interest: None


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Aqueous, light petroleum, chloroform, alcohol, benzene and acetone extracts of the leaves of Coccinia indica  (Family: Cucurbitaceae) were screened for antihepatotoxic activity. The extracts were given after the liver was damaged with Ccl4 Liver function was assessed based on liver to body weight ratio pentobarbitone sleep time, serum levels of transaminase (SGPT, SGOT), alkaline phosphatase (SALP and bilirubin. Alcohol and light petroleum was found to have good anti-hepatotoxic activity.


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