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Year : 2000  |  Volume : 20  |  Issue : 1  |  Page : 44-47

Antiurolithiatic activity of Coleus aromaticus Benth. In Rats

1 Department of Kayachikitsa, Institute of PG Ayurvedic Education & Research, Calcutta-9, India
2 Department of Pharmacology, University College of Medicine, Calcutta-20, India
3 Department of Urology, IPGMER, Calcutta-20, India

Correspondence Address:
R B Ghosh
Department of Kayachikitsa, Institute of PG Ayurvedic Education & Research, Calcutta-9
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Source of Support: None, Conflict of Interest: None

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Water extract of the leaves of Coleus aromaticus  Benth. Was tested for its antiurolithiatic activity against calcium oxalate stones in male albino rats. Calcium oxalate stones were induced by feeding 3% w/w sodium oxalate along with normal feed. The water extract of coleus aromaticus (0.5 g/kg and 1.0 g/kg, once, orally for 30 days) was found to be effective in reducing deposition of calcium oxalate. Hence, it is suggested, coleus aromaticus leaves may be effective in the therapy of calcium oxalate stone formation in kidney and urinary tract.

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