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| Year : 1998 | Volume
: 18
| Issue : 1 | Page : 52-57 |
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Pharmacological investigations on Aglaia roxburghiana (w. &.a) Miq. Var. beddomei leaves
S Janaki1, S Vijayasekaran2, R Bima Rao3
1 Department of pharmacology, sri ramachandra medical college & research institute, (Deemed University), Porur, Chennai – 600 116, Tamil Nadu, India
2 Institute of pharmacology, Chennai medical college, Chennai – 600 003, India
3 Captain Srinivasa Murti drug research institute for Ayurveda, Arumbakkam, Chennai – 600 106, India
Correspondence Address:
S Janaki
Department of pharmacology, sri ramachandra medical college & research institute, (Deemed University), Porur, Chennai – 600 116, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Aglaia roxburghiana is a traditional remedy for a variety of diseases. The ethanolic extract of the leaves was screened for related activities were upon it exhibited significant anti-inflammatory activity in rats in acute and chronic models. There was no acute toxicity in mice upto 2g/kg. The extract protected the mast cell deregulation by compound 48/80 and inhibited histamine induced contractions in guinea pig ileum. The data obtained in this study suggest that the extract ma act by stabilizing mast cells ad blocking histamine receptors. |
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