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Year : 1995  |  Volume : 15  |  Issue : 2  |  Page : 110-114

Effect of short duration caffeine treatment on the jejunum of adult Albino rats

Department of zoology, Bharathiar University, Coimbatore - 641 046, India

Correspondence Address:
R Pushpalatha
Department of zoology, Bharathiar University, Coimbatore - 641 046
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Source of Support: None, Conflict of Interest: None

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The effect of the short duration (21 days) of caffeine at two different doses (12 mg & 30 mg/kg body weight/day) on the activities of adenosine triphosphatases in jejunum was studied. The activity of Na+, K+ -dependent ATP-ase was reduced significantly in the upper jejunal mucosal and serosal layers of low an high dose groups. Such effect was observed only in the lower jejunal serosal layer while a marked reduction in the activity of Mg2+ATP -ase was seen in mucosal and serosal layers of the jejunum at both doses. There was a significant increase in the activities of Ca2+-dependent and HCO3-dependent ATP -ases in these regions of the lower jejunum.

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