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| Year : 1993 | Volume
: 13
| Issue : 1 | Page : 137-142 |
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Pharmacological studies of Araucaria bidwilli hook
S Dhanasekaran1, S Ravishankar1, K Sumithra Devi1, B Suresh1, M Sethuraman2, S Rajan3
1 Department of Pharmacology, J.S.S. College of Pharmacy, Udhagamandalam - 643 001, India
2 Department of Medical Anthropology, Tamil University, M. Palada, Udhagamandalam - 643 004, India
3 Survey of Medicinal Plant & Collection Unit, 112, Government Arts College Campus, Udhagamandalam - 643 002, India
Correspondence Address:
S Dhanasekaran
Department of Pharmacology, J.S.S. College of Pharmacy, Udhagamandalam - 643 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Leaf and oleoresin fractions of both alcoholic and petroleum ether extracts of Araucaria bidwillii exhibited significant prolongation of pentobarbitones sleeping time at a dose of 300 and 100 mg/kg body weight respectively in mice. This effect is more pronounced for oleoresin than the leaf extracts. Further, the two extracts seem to possess analgesic effect comparable to aspirin by writing method. The analgesic activity is found to be higher in oleoresin than the leaf extracts. Both the extracts are found to show high anti inflammatory activity comparable to phenylbutzaone by cotton pellet granuloma method. |
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