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ARTICLE
Year : 1992  |  Volume : 12  |  Issue : 1  |  Page : 251-256

Antimicrobial activity of chemoconstituents of roots of Salacia macrosperma


University College of Pharmaceutical Sciences, Kokatiya University, Warangal - 560 009, Andhra Pradesh, India

Correspondence Address:
V Venkatesarulu
University College of Pharmaceutical Sciences, Kokatiya University, Warangal - 560 009, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


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The ethanolic extract of roots of Salacia macrosperma (Hippocrataceae) exhibited significant in vitro antimicrobial activity. The ethanolic extract was fractionated with different solvents and all the fractions were screened for their antimicrobial spectrum against eight gram-positive, five gram-negative and ten fungal strains. Chloroform fraction followed by benzene fraction of enthanolic extract showed significant antimicrobial effect against all the microorganisms tested. The dose-dependent activity of fractions was evaluated against selected microbial strains and compared with appropriate standards.


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