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Year : 1989  |  Volume : 8  |  Issue : 3  |  Page : 212-219

Adaptogenic activity of seeds of trichopus zeylanicus gaertn, the ginseng of Kerala

1 Regional Research Laboratory (CSIR), Jammu Tawi 180 001, India
2 Regional Research Centre, Drug Research (CCRAS), Trivandrum 695 012, India

Correspondence Address:
Avinash K Sharma
Regional Research Laboratory (CSIR), Jammu Tawi 180 001
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Source of Support: None, Conflict of Interest: None

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The alchoholic extract of seeds of Trichopus zeylanicus showed a potent adaptogenic or antistress properties against a variety of stresses in both rats an dmice. The extract increased the swimming performance of normal and adrenalectomized mice. Significantly; prevented a variety of stress and chemical induced ulcerations in rats and also prevented milk-induced leucocytosis in mice. The extract further reduced the gastric secretary clume, PH and acid output in pylorusligated rat stomach. No mortalitiy was observed upto a dose of 3 g/kg per oral in mice. The study indicated that trichopus zeylanicus seeds induce a state of nonspecific increased resistance against a variety of stress induced biological changes in animals.

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