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| Year : 1989 | Volume
: 8
| Issue : 3 | Page : 212-219 |
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Adaptogenic activity of seeds of trichopus zeylanicus gaertn, the ginseng of Kerala
Avinash K Sharma1, P Pushpangadan1, CL Chopra1, S Rajasekharan2, L Sarada Amma2
1 Regional Research Laboratory (CSIR), Jammu Tawi 180 001, India
2 Regional Research Centre, Drug Research (CCRAS), Trivandrum 695 012, India
Correspondence Address:
Avinash K Sharma
Regional Research Laboratory (CSIR), Jammu Tawi 180 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
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The alchoholic extract of seeds of Trichopus zeylanicus showed a potent adaptogenic or antistress properties against a variety of stresses in both rats an dmice. The extract increased the swimming performance of normal and adrenalectomized mice. Significantly; prevented a variety of stress and chemical induced ulcerations in rats and also prevented milk-induced leucocytosis in mice. The extract further reduced the gastric secretary clume, PH and acid output in pylorusligated rat stomach. No mortalitiy was observed upto a dose of 3 g/kg per oral in mice. The study indicated that trichopus zeylanicus seeds induce a state of nonspecific increased resistance against a variety of stress induced biological changes in animals. |
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