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Year : 1989  |  Volume : 8  |  Issue : 3  |  Page : 207-211

Antiulcer activity of agnitundirasa and its comparison with cimetidine in shay rat

Department of Pharmaceutical sciences, Andhra University, waltair 530 003, India

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S Satyanarayana
Department of Pharmaceutical sciences, Andhra University, waltair 530 003
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Source of Support: None, Conflict of Interest: None

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Agnitundirasa was tested for antigastric ulcer activity in shay rat model. Oral dose of 10 mg/kg reduced the ulceration in shay rat. With 20mg/kg dose the ulceration was completely absent. The antigastric ulcer activity of agnitundirasa (20 mg/kg) was found to be equal to the effect produced by cimetidine (20 mg/kg). The reduction in gastric acidity was more with cimetidine and the reduction in peptic activity was more with agnitundirasa.

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